A Case of Anti-SAE1 Dermatomyositis

Introduction. Anti-SAE1 antibodies have a low prevalence in dermatomyositis patients. Case Description. A 61-year-old woman presented with progressive shortness of breath, arthralgia, heliotrope rash, Gottron’s papules, and erythematous rash. She had an interstitial lung disease (ILD) with a signifi...

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Main Authors: Max de Vries, Marco W. J. Schreurs, Els J. M. Ahsmann, Marcela Spee-Dropkova, Faiz Karim
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Immunology
Online Access:http://dx.doi.org/10.1155/2022/9000608
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author Max de Vries
Marco W. J. Schreurs
Els J. M. Ahsmann
Marcela Spee-Dropkova
Faiz Karim
author_facet Max de Vries
Marco W. J. Schreurs
Els J. M. Ahsmann
Marcela Spee-Dropkova
Faiz Karim
author_sort Max de Vries
collection DOAJ
description Introduction. Anti-SAE1 antibodies have a low prevalence in dermatomyositis patients. Case Description. A 61-year-old woman presented with progressive shortness of breath, arthralgia, heliotrope rash, Gottron’s papules, and erythematous rash. She had an interstitial lung disease (ILD) with a significant decrease in lung function. There was no muscle involvement. Immunological laboratory test results showed strongly positive anti-SAE1 antibodies. Glucocorticoid treatment resulted in remission of dermatomyositis. Conclusion. Anti-SAE antibodies in dermatomyositis patients are closely linked to unique clinical features.
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institution Kabale University
issn 2090-6617
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series Case Reports in Immunology
spelling doaj-art-045e1e9bbe3e4f83abed4b33682b6b842025-02-03T05:45:28ZengWileyCase Reports in Immunology2090-66172022-01-01202210.1155/2022/9000608A Case of Anti-SAE1 DermatomyositisMax de Vries0Marco W. J. Schreurs1Els J. M. Ahsmann2Marcela Spee-Dropkova3Faiz Karim4Department of Internal MedicineDepartment of ImmunologyDepartment of Clinical PathologyDepartment of RadiologyDepartment of Internal MedicineIntroduction. Anti-SAE1 antibodies have a low prevalence in dermatomyositis patients. Case Description. A 61-year-old woman presented with progressive shortness of breath, arthralgia, heliotrope rash, Gottron’s papules, and erythematous rash. She had an interstitial lung disease (ILD) with a significant decrease in lung function. There was no muscle involvement. Immunological laboratory test results showed strongly positive anti-SAE1 antibodies. Glucocorticoid treatment resulted in remission of dermatomyositis. Conclusion. Anti-SAE antibodies in dermatomyositis patients are closely linked to unique clinical features.http://dx.doi.org/10.1155/2022/9000608
spellingShingle Max de Vries
Marco W. J. Schreurs
Els J. M. Ahsmann
Marcela Spee-Dropkova
Faiz Karim
A Case of Anti-SAE1 Dermatomyositis
Case Reports in Immunology
title A Case of Anti-SAE1 Dermatomyositis
title_full A Case of Anti-SAE1 Dermatomyositis
title_fullStr A Case of Anti-SAE1 Dermatomyositis
title_full_unstemmed A Case of Anti-SAE1 Dermatomyositis
title_short A Case of Anti-SAE1 Dermatomyositis
title_sort case of anti sae1 dermatomyositis
url http://dx.doi.org/10.1155/2022/9000608
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