Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus)
The current study was conducted to investigate the influences of dietary compound acidifier (CA, Formic acid (45 %), malic acid (0.3 %), Fumaric acid (0.6 %) and Succinic acid (0.6 %), Biomin Feed Additives (Shanghai) Ltd) on the growth, anti-oxidation, immunity, and intestinal health of channel cat...
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Elsevier
2025-03-01
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| Series: | Aquaculture Reports |
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| author | Junyu Yan Kai Luo Bo Wang Jiaxin He Can Li Jiang Zhou Wenhao Lai Xin Zhou Jingwei Ye Mingzhu Pan Yingbing Su Weihua Gao Kai Guo Chengmin Zhao |
| author_facet | Junyu Yan Kai Luo Bo Wang Jiaxin He Can Li Jiang Zhou Wenhao Lai Xin Zhou Jingwei Ye Mingzhu Pan Yingbing Su Weihua Gao Kai Guo Chengmin Zhao |
| author_sort | Junyu Yan |
| collection | DOAJ |
| description | The current study was conducted to investigate the influences of dietary compound acidifier (CA, Formic acid (45 %), malic acid (0.3 %), Fumaric acid (0.6 %) and Succinic acid (0.6 %), Biomin Feed Additives (Shanghai) Ltd) on the growth, anti-oxidation, immunity, and intestinal health of channel catfish (Ictalurus punctatus). Six experimental diets (about 36 % crude protein and 5 % crude lipid) were prepared with graded levels of dietary CA (0 (control), 0.05 %, 0.10 %, 0.20 %, 0.40 %, and 0.80 %). A total of 648 fish with similar initial body weight (143.77 ± 0.73 g) were randomly placed into 18 tanks, with 36 fish in each tank. Fish were hand-fed to apparent satiation thrice daily for 72 days (water temperature was 25–27℃). The results showed that the WGR (weight giant rate) and SGR (specific growth rate) of channel catfish in the 0.10 % group were significantly increased compared with the control group (P < 0.05). The broken line model revealed that 0.0863 % of dietary CA was recommended for optimal SGR. The SOD (superoxide dismutase) activity and MDA (malondialdehyde) content in the serum in the 0.10 % groups were remarkably increased and decreased compared with the control group, respectively (P < 0.05). The ACP (acid phosphatase), LZM (lysozyme) activities and ALB (albumin) contents in the serum were significantly increased after supplementation of 0.10–0.40 %, 0.10–0.20 % and 0.40–0.80 % of dietary CA, respectively (P < 0.05). The AKP (alkaline phosphatase) activity in the serum in the 0.05 % and 0.10 % groups was decreased compared with other groups (P < 0.05). The GOT (glutamic oxalacetic transaminase) and GPT (glutamic pyruvic transaminase) activities in the serum notably decreased by 0.10–0.20 % and 0.05 % of dietary CA, respectively (P < 0.05). The T-CHO (total cholesterol) and HDL-C (high density lipoprotein cholesterol) contents in the serum increased by 0.80 % and 0.05 %-0.80 % of dietary CA (P < 0.05). The TG (triglyceride) content in the serum was lowest in the 0.10 % group. The expression levels of gh (growth hormone), ghr (growth hormone receptor), igf-1 (insulin-like growth factors 1), igf-2, igfbp-1 (insulin-like growth factor-binding proteins-1), igfbp-2 and igfbp-3 in the liver of the 0.10 % group were significantly higher than the control and 0.08 % groups (P < 0.05). The level of tgf-β (transforming growth factor beta), il-10 (interleukin 10), caspase3, caspase7, caspase9, occludin, zo-1 (zonula occludens-1), zo-2, claudin-12, claudin-15a, claudin-15b in the intestine of the 0.10 % group significantly increased compared with the control group (P < 0.05). Supplementation of 0.10 % dietary CA could improve the microbial diversity in the intestine of channel catfish. In conclusion, adding 0.10 % of dietary CA to the diet could improve the growth performance, anti-oxidative capacity, immunity, and intestinal health of channel catfish. Based on the SGR, the recommended optimal level of CA for channel catfish was 0.0863 %. The mechanisms regulating the growth-promoting and health-improving effects of CA on channel catfish need to be further investigated. |
| format | Article |
| id | doaj-art-044ef51b39e847208fe64b257850e927 |
| institution | Kabale University |
| issn | 2352-5134 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
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| series | Aquaculture Reports |
| spelling | doaj-art-044ef51b39e847208fe64b257850e9272025-02-06T05:12:11ZengElsevierAquaculture Reports2352-51342025-03-0140102577Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus)Junyu Yan0Kai Luo1Bo Wang2Jiaxin He3Can Li4Jiang Zhou5Wenhao Lai6Xin Zhou7Jingwei Ye8Mingzhu Pan9Yingbing Su10Weihua Gao11Kai Guo12Chengmin Zhao13Hubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, ChinaHubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, ChinaHubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, ChinaHubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, ChinaHubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, ChinaHubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, ChinaHubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, ChinaHubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, ChinaHubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, ChinaDepartment of Ocean Technology, College of Marine and Biology Engineering, Yancheng Institute of Technology, Yancheng, ChinaHubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, China; Corresponding authors.Hubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, China; Corresponding authors.Department of Animal Nutrition and Health, Dsm-Firmenich (China) Co., Ltd, Shanghai, ChinaHubei Xiaobenyu Agricultural Development Co., Ltd, ChinaThe current study was conducted to investigate the influences of dietary compound acidifier (CA, Formic acid (45 %), malic acid (0.3 %), Fumaric acid (0.6 %) and Succinic acid (0.6 %), Biomin Feed Additives (Shanghai) Ltd) on the growth, anti-oxidation, immunity, and intestinal health of channel catfish (Ictalurus punctatus). Six experimental diets (about 36 % crude protein and 5 % crude lipid) were prepared with graded levels of dietary CA (0 (control), 0.05 %, 0.10 %, 0.20 %, 0.40 %, and 0.80 %). A total of 648 fish with similar initial body weight (143.77 ± 0.73 g) were randomly placed into 18 tanks, with 36 fish in each tank. Fish were hand-fed to apparent satiation thrice daily for 72 days (water temperature was 25–27℃). The results showed that the WGR (weight giant rate) and SGR (specific growth rate) of channel catfish in the 0.10 % group were significantly increased compared with the control group (P < 0.05). The broken line model revealed that 0.0863 % of dietary CA was recommended for optimal SGR. The SOD (superoxide dismutase) activity and MDA (malondialdehyde) content in the serum in the 0.10 % groups were remarkably increased and decreased compared with the control group, respectively (P < 0.05). The ACP (acid phosphatase), LZM (lysozyme) activities and ALB (albumin) contents in the serum were significantly increased after supplementation of 0.10–0.40 %, 0.10–0.20 % and 0.40–0.80 % of dietary CA, respectively (P < 0.05). The AKP (alkaline phosphatase) activity in the serum in the 0.05 % and 0.10 % groups was decreased compared with other groups (P < 0.05). The GOT (glutamic oxalacetic transaminase) and GPT (glutamic pyruvic transaminase) activities in the serum notably decreased by 0.10–0.20 % and 0.05 % of dietary CA, respectively (P < 0.05). The T-CHO (total cholesterol) and HDL-C (high density lipoprotein cholesterol) contents in the serum increased by 0.80 % and 0.05 %-0.80 % of dietary CA (P < 0.05). The TG (triglyceride) content in the serum was lowest in the 0.10 % group. The expression levels of gh (growth hormone), ghr (growth hormone receptor), igf-1 (insulin-like growth factors 1), igf-2, igfbp-1 (insulin-like growth factor-binding proteins-1), igfbp-2 and igfbp-3 in the liver of the 0.10 % group were significantly higher than the control and 0.08 % groups (P < 0.05). The level of tgf-β (transforming growth factor beta), il-10 (interleukin 10), caspase3, caspase7, caspase9, occludin, zo-1 (zonula occludens-1), zo-2, claudin-12, claudin-15a, claudin-15b in the intestine of the 0.10 % group significantly increased compared with the control group (P < 0.05). Supplementation of 0.10 % dietary CA could improve the microbial diversity in the intestine of channel catfish. In conclusion, adding 0.10 % of dietary CA to the diet could improve the growth performance, anti-oxidative capacity, immunity, and intestinal health of channel catfish. Based on the SGR, the recommended optimal level of CA for channel catfish was 0.0863 %. The mechanisms regulating the growth-promoting and health-improving effects of CA on channel catfish need to be further investigated.http://www.sciencedirect.com/science/article/pii/S2352513424006653Enzyme activityGene expressionIntestinal barrierIntestinal microbiome |
| spellingShingle | Junyu Yan Kai Luo Bo Wang Jiaxin He Can Li Jiang Zhou Wenhao Lai Xin Zhou Jingwei Ye Mingzhu Pan Yingbing Su Weihua Gao Kai Guo Chengmin Zhao Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) Aquaculture Reports Enzyme activity Gene expression Intestinal barrier Intestinal microbiome |
| title | Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) |
| title_full | Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) |
| title_fullStr | Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) |
| title_full_unstemmed | Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) |
| title_short | Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) |
| title_sort | effects of dietary compound acidifier biomin on the growth anti oxidation immunity and intestinal health of juvenile channel catfish ictalurus punctatus |
| topic | Enzyme activity Gene expression Intestinal barrier Intestinal microbiome |
| url | http://www.sciencedirect.com/science/article/pii/S2352513424006653 |
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