Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil
Brazil has reported more than 1,600 cases of hantavirus cardiopulmonary syndrome (HPS) since 1993, with a 39% rate of reported fatalities. Using a recombinant nucleocapsid protein of Araraquara virus, we performed ELISA to detect IgG antibodies against hantavirus in human sera. The aim of this study...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Advances in Virology |
| Online Access: | http://dx.doi.org/10.1155/2016/8628949 |
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| author | Felipe Alves Morais Alexandre Pereira Aparecida Santo Pietro Pereira Marcos Lazaro Moreli Luís Marcelo Aranha Camargo Marcello Schiavo Nardi Cristina Farah Tófoli Jansen Araujo Lilia Mara Dutra Tatiana Lopes Ometto Renata Hurtado Fábio Carmona de Jesus Maués Tiene Zingano Hinke Sati Jaber Mahmud Monica Correia Lima Luiz Tadeu Moraes Figueiredo Edison Luiz Durigon |
| author_facet | Felipe Alves Morais Alexandre Pereira Aparecida Santo Pietro Pereira Marcos Lazaro Moreli Luís Marcelo Aranha Camargo Marcello Schiavo Nardi Cristina Farah Tófoli Jansen Araujo Lilia Mara Dutra Tatiana Lopes Ometto Renata Hurtado Fábio Carmona de Jesus Maués Tiene Zingano Hinke Sati Jaber Mahmud Monica Correia Lima Luiz Tadeu Moraes Figueiredo Edison Luiz Durigon |
| author_sort | Felipe Alves Morais |
| collection | DOAJ |
| description | Brazil has reported more than 1,600 cases of hantavirus cardiopulmonary syndrome (HPS) since 1993, with a 39% rate of reported fatalities. Using a recombinant nucleocapsid protein of Araraquara virus, we performed ELISA to detect IgG antibodies against hantavirus in human sera. The aim of this study was to analyze hantavirus antibody levels in inhabitants from a tropical area (Amazon region) in Rondônia state and a subtropical (Atlantic Rain Forest) region in São Paulo state, Brazil. A total of 1,310 serum samples were obtained between 2003 and 2008 and tested by IgG-ELISA, and 82 samples (6.2%), of which 62 were from the tropical area (5.8%) and 20 from the subtropical area (8.3%), tested positive. Higher levels of hantavirus antibody were observed in inhabitants of the populous subtropical areas compared with those from the tropical areas in Brazil. |
| format | Article |
| id | doaj-art-043f9d14c7294c5692ab0138771c3c9a |
| institution | Kabale University |
| issn | 1687-8639 1687-8647 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Virology |
| spelling | doaj-art-043f9d14c7294c5692ab0138771c3c9a2025-02-03T01:01:41ZengWileyAdvances in Virology1687-86391687-86472016-01-01201610.1155/2016/86289498628949Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of BrazilFelipe Alves Morais0Alexandre Pereira1Aparecida Santo Pietro Pereira2Marcos Lazaro Moreli3Luís Marcelo Aranha Camargo4Marcello Schiavo Nardi5Cristina Farah Tófoli6Jansen Araujo7Lilia Mara Dutra8Tatiana Lopes Ometto9Renata Hurtado10Fábio Carmona de Jesus Maués11Tiene Zingano Hinke12Sati Jaber Mahmud13Monica Correia Lima14Luiz Tadeu Moraes Figueiredo15Edison Luiz Durigon16Laboratório de Virologia Clínica e Molecular, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05508-900 São Paulo, SP, BrazilLaboratório de Genética, Instituto Butantan, 05503-900 São Paulo, SP, BrazilLaboratório de Genética, Instituto Butantan, 05503-900 São Paulo, SP, BrazilLaboratório de Virologia, Universidade Federal de Goiás, 75801-615 Jatai, GO, BrazilDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05389-970 São Paulo, SP, BrazilInstituto de Pesquisa Ecológica (IPE), 12960-000 Nazaré Paulista, SP, BrazilInstituto de Pesquisa Ecológica (IPE), 12960-000 Nazaré Paulista, SP, BrazilLaboratório de Virologia Clínica e Molecular, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05508-900 São Paulo, SP, BrazilLaboratório de Virologia Clínica e Molecular, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05508-900 São Paulo, SP, BrazilLaboratório de Virologia Clínica e Molecular, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05508-900 São Paulo, SP, BrazilLaboratório de Virologia Clínica e Molecular, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05508-900 São Paulo, SP, BrazilLaboratório de Virologia Clínica e Molecular, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05508-900 São Paulo, SP, BrazilDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05389-970 São Paulo, SP, BrazilDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05389-970 São Paulo, SP, BrazilDepartamento Municipal de Saúde, 11950-000 Prefeitura de Cajati, SP, BrazilCentro de Pesquisa em Virologia da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, 14049-900 Ribeirão Preto, SP, BrazilLaboratório de Virologia Clínica e Molecular, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 05508-900 São Paulo, SP, BrazilBrazil has reported more than 1,600 cases of hantavirus cardiopulmonary syndrome (HPS) since 1993, with a 39% rate of reported fatalities. Using a recombinant nucleocapsid protein of Araraquara virus, we performed ELISA to detect IgG antibodies against hantavirus in human sera. The aim of this study was to analyze hantavirus antibody levels in inhabitants from a tropical area (Amazon region) in Rondônia state and a subtropical (Atlantic Rain Forest) region in São Paulo state, Brazil. A total of 1,310 serum samples were obtained between 2003 and 2008 and tested by IgG-ELISA, and 82 samples (6.2%), of which 62 were from the tropical area (5.8%) and 20 from the subtropical area (8.3%), tested positive. Higher levels of hantavirus antibody were observed in inhabitants of the populous subtropical areas compared with those from the tropical areas in Brazil.http://dx.doi.org/10.1155/2016/8628949 |
| spellingShingle | Felipe Alves Morais Alexandre Pereira Aparecida Santo Pietro Pereira Marcos Lazaro Moreli Luís Marcelo Aranha Camargo Marcello Schiavo Nardi Cristina Farah Tófoli Jansen Araujo Lilia Mara Dutra Tatiana Lopes Ometto Renata Hurtado Fábio Carmona de Jesus Maués Tiene Zingano Hinke Sati Jaber Mahmud Monica Correia Lima Luiz Tadeu Moraes Figueiredo Edison Luiz Durigon Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil Advances in Virology |
| title | Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil |
| title_full | Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil |
| title_fullStr | Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil |
| title_full_unstemmed | Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil |
| title_short | Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil |
| title_sort | serological survey of hantavirus in inhabitants from tropical and subtropical areas of brazil |
| url | http://dx.doi.org/10.1155/2016/8628949 |
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