Hypertension Subtypes among Thai Hypertensives: An Analysis of Telehealth-Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot Project

Background. White-coat hypertension (HT), masked HT, HT with white-coat effect, and masked uncontrolled HT are well-recognized problems of over- and undertreatment of high blood pressure in real-life practice. However, little is known about the true prevalence in Thailand. Objectives. To examine the...

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Main Authors: Sakolwat Montrivade, Pairoj Chattranukulchai, Sarawut Siwamogsatham, Yongkasem Vorasettakarnkij, Witthawat Naeowong, Patchaya Boonchayaanant, Anut Sakulsupsiri, Aekarach Ariyachaipanich, Vorarit Lertsuwunseri, Voravut Rungpradubvong, Sudarat Satitthummanid, Sarinya Puwanant, Somchai Prechawat, Suphot Srimahachota, Jarkarpun Chaipromprasit, Wacin Buddhari, Smonporn Boonyaratavej, Surapun Sitthisook, Peera Buranakitjaroen, Apichard Sukonthasarn, Somkiat Sangwatanaroj
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2020/3261408
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author Sakolwat Montrivade
Pairoj Chattranukulchai
Sarawut Siwamogsatham
Yongkasem Vorasettakarnkij
Witthawat Naeowong
Patchaya Boonchayaanant
Anut Sakulsupsiri
Aekarach Ariyachaipanich
Vorarit Lertsuwunseri
Voravut Rungpradubvong
Sudarat Satitthummanid
Sarinya Puwanant
Somchai Prechawat
Suphot Srimahachota
Jarkarpun Chaipromprasit
Wacin Buddhari
Smonporn Boonyaratavej
Surapun Sitthisook
Peera Buranakitjaroen
Apichard Sukonthasarn
Somkiat Sangwatanaroj
author_facet Sakolwat Montrivade
Pairoj Chattranukulchai
Sarawut Siwamogsatham
Yongkasem Vorasettakarnkij
Witthawat Naeowong
Patchaya Boonchayaanant
Anut Sakulsupsiri
Aekarach Ariyachaipanich
Vorarit Lertsuwunseri
Voravut Rungpradubvong
Sudarat Satitthummanid
Sarinya Puwanant
Somchai Prechawat
Suphot Srimahachota
Jarkarpun Chaipromprasit
Wacin Buddhari
Smonporn Boonyaratavej
Surapun Sitthisook
Peera Buranakitjaroen
Apichard Sukonthasarn
Somkiat Sangwatanaroj
author_sort Sakolwat Montrivade
collection DOAJ
description Background. White-coat hypertension (HT), masked HT, HT with white-coat effect, and masked uncontrolled HT are well-recognized problems of over- and undertreatment of high blood pressure in real-life practice. However, little is known about the true prevalence in Thailand. Objectives. To examine the prevalence and characteristics of each HT subtype defined by mean home blood pressure (HBP) and clinic blood pressure (CBP) using telemonitoring technology in Thai hypertensives. Methods. A multicenter, observational study included adult hypertensives who had been diagnosed for at least 3 months based on CBP without the adoption of HBP monitoring. All patients were instructed to manually measure their HBP twice a day for the duration of at least one week using the same validated automated, oscillometric telemonitoring devices (Uright model TD-3128, TaiDoc Corporation, Taiwan). The HBP, CBP, and baseline demographic data were recorded on the web-based system. HT subtypes were classified according to the treatment status, CBP (≥or <140/90 mmHg), and mean HBP (≥or <135/85 mmHg) into the following eight subtypes: in nonmedicated hypertensives, there are four subtypes that are normotension, white-coat HT, masked HT, and sustained HT; in treated hypertensives, there are four subtypes that are well-controlled HT, HT with white-coat effect, masked uncontrolled HT, and sustained HT. Results. Of the 1,184 patients (mean age 58 ± 12.7 years, 59% women) from 46 hospitals, 1,040 (87.8%) were taking antihypertensive agents. The majority of them were enrolled from primary care hospitals (81%). In the nonmedicated group, the prevalence of white-coat and masked HT was 25.7% and 7.0%, respectively. Among the treated patients, the HT with white-coat effect was found in 23.3% while 46.7% had uncontrolled HBP (a combination of the masked uncontrolled HT (9.6%) and sustained HT (37.1%)). In the medicated older subgroup (n = 487), uncontrolled HBP was more prevalent in male than in female (53.6% vs. 42.4%, p=0.013). Conclusions. This is the first nationwide study in Thailand to examine the prevalence of HT subtypes. Almost one-fourth had white-coat HT or HT with white-coat effect. Approximately half of the treated patients especially in the older males had uncontrolled HBP requiring more intensive interventions. These results emphasize the role of HBP monitoring for appropriate HT diagnosis and management. The cost-effectiveness of utilizing THAI HBPM in routine practice needs to be examined in the future study.
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spelling doaj-art-043d45e72ff349dfb59e8c670f23cd9e2025-02-03T05:44:11ZengWileyInternational Journal of Hypertension2090-03842090-03922020-01-01202010.1155/2020/32614083261408Hypertension Subtypes among Thai Hypertensives: An Analysis of Telehealth-Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot ProjectSakolwat Montrivade0Pairoj Chattranukulchai1Sarawut Siwamogsatham2Yongkasem Vorasettakarnkij3Witthawat Naeowong4Patchaya Boonchayaanant5Anut Sakulsupsiri6Aekarach Ariyachaipanich7Vorarit Lertsuwunseri8Voravut Rungpradubvong9Sudarat Satitthummanid10Sarinya Puwanant11Somchai Prechawat12Suphot Srimahachota13Jarkarpun Chaipromprasit14Wacin Buddhari15Smonporn Boonyaratavej16Surapun Sitthisook17Peera Buranakitjaroen18Apichard Sukonthasarn19Somkiat Sangwatanaroj20Division of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Hospital and Ambulatory Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Hospital and Ambulatory Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Hospital and Ambulatory Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandPharmacy Department, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandDepartment of Medicine, Siriraj Hospital, Mahidol University, 10700 Bangkok, ThailandThai Hypertension Society, 10310 Bangkok, ThailandDivision of Cardiovascular Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 10330 Bangkok, ThailandBackground. White-coat hypertension (HT), masked HT, HT with white-coat effect, and masked uncontrolled HT are well-recognized problems of over- and undertreatment of high blood pressure in real-life practice. However, little is known about the true prevalence in Thailand. Objectives. To examine the prevalence and characteristics of each HT subtype defined by mean home blood pressure (HBP) and clinic blood pressure (CBP) using telemonitoring technology in Thai hypertensives. Methods. A multicenter, observational study included adult hypertensives who had been diagnosed for at least 3 months based on CBP without the adoption of HBP monitoring. All patients were instructed to manually measure their HBP twice a day for the duration of at least one week using the same validated automated, oscillometric telemonitoring devices (Uright model TD-3128, TaiDoc Corporation, Taiwan). The HBP, CBP, and baseline demographic data were recorded on the web-based system. HT subtypes were classified according to the treatment status, CBP (≥or <140/90 mmHg), and mean HBP (≥or <135/85 mmHg) into the following eight subtypes: in nonmedicated hypertensives, there are four subtypes that are normotension, white-coat HT, masked HT, and sustained HT; in treated hypertensives, there are four subtypes that are well-controlled HT, HT with white-coat effect, masked uncontrolled HT, and sustained HT. Results. Of the 1,184 patients (mean age 58 ± 12.7 years, 59% women) from 46 hospitals, 1,040 (87.8%) were taking antihypertensive agents. The majority of them were enrolled from primary care hospitals (81%). In the nonmedicated group, the prevalence of white-coat and masked HT was 25.7% and 7.0%, respectively. Among the treated patients, the HT with white-coat effect was found in 23.3% while 46.7% had uncontrolled HBP (a combination of the masked uncontrolled HT (9.6%) and sustained HT (37.1%)). In the medicated older subgroup (n = 487), uncontrolled HBP was more prevalent in male than in female (53.6% vs. 42.4%, p=0.013). Conclusions. This is the first nationwide study in Thailand to examine the prevalence of HT subtypes. Almost one-fourth had white-coat HT or HT with white-coat effect. Approximately half of the treated patients especially in the older males had uncontrolled HBP requiring more intensive interventions. These results emphasize the role of HBP monitoring for appropriate HT diagnosis and management. The cost-effectiveness of utilizing THAI HBPM in routine practice needs to be examined in the future study.http://dx.doi.org/10.1155/2020/3261408
spellingShingle Sakolwat Montrivade
Pairoj Chattranukulchai
Sarawut Siwamogsatham
Yongkasem Vorasettakarnkij
Witthawat Naeowong
Patchaya Boonchayaanant
Anut Sakulsupsiri
Aekarach Ariyachaipanich
Vorarit Lertsuwunseri
Voravut Rungpradubvong
Sudarat Satitthummanid
Sarinya Puwanant
Somchai Prechawat
Suphot Srimahachota
Jarkarpun Chaipromprasit
Wacin Buddhari
Smonporn Boonyaratavej
Surapun Sitthisook
Peera Buranakitjaroen
Apichard Sukonthasarn
Somkiat Sangwatanaroj
Hypertension Subtypes among Thai Hypertensives: An Analysis of Telehealth-Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot Project
International Journal of Hypertension
title Hypertension Subtypes among Thai Hypertensives: An Analysis of Telehealth-Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot Project
title_full Hypertension Subtypes among Thai Hypertensives: An Analysis of Telehealth-Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot Project
title_fullStr Hypertension Subtypes among Thai Hypertensives: An Analysis of Telehealth-Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot Project
title_full_unstemmed Hypertension Subtypes among Thai Hypertensives: An Analysis of Telehealth-Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot Project
title_short Hypertension Subtypes among Thai Hypertensives: An Analysis of Telehealth-Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot Project
title_sort hypertension subtypes among thai hypertensives an analysis of telehealth assisted instrument in home blood pressure monitoring nationwide pilot project
url http://dx.doi.org/10.1155/2020/3261408
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