Phase II study with sorafenib plus radiotherapy for advanced HCC with portal and/or hepatic vein tumor thrombosis

Phase II study with sorafenib plus radiotherapy for advanced HCC with portal and/or hepatic vein tumor thrombosis

Background & Aims: Portal and hepatic vein tumor thrombosis is associated with inferior outcomes in patients with hepatocellular carcinoma (HCC), and systemic treatment alone is often insufficient. This phase II trial evaluated the efficacy and safety of combining sorafenib with radiotherapy...

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Main Authors: Yirui Zhai, Liming Wang, Hong Zhao, Fan Wu, Lingxia Xin, Feng Ye, Wei Sun, Yan Song, Lijuan Niu, Huiying Zeng, Jingbo Wang, Yuan Tang, Yongwen Song, Yueping Liu, Hui Fang, Ningning Lu, Hao Jing, Shunan Qi, Wenwen Zhang, Shulian Wang, Ye-Xiong Li, Jianxiong Wu, Bo Chen
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:JHEP Reports
Subjects:
Sorafenib
Radiotherapy
Hepatocellular carcinoma
Tumor thrombosis
Online Access:http://www.sciencedirect.com/science/article/pii/S258955592400291X
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