Diagnosis of Parasitic Diseases: Old and New Approaches
Methods for the diagnosis of infectious diseases have stagnated in the last 20–30 years. Few major advances in clinical diagnostic testing have been made since the introduction of PCR, although new technologies are being investigated. Many tests that form the backbone of the “modern” microbiology la...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Interdisciplinary Perspectives on Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2009/278246 |
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| _version_ | 1832558772124385280 |
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| author | Momar Ndao |
| author_facet | Momar Ndao |
| author_sort | Momar Ndao |
| collection | DOAJ |
| description | Methods for the diagnosis of infectious diseases have stagnated in the last 20–30 years. Few major advances in clinical diagnostic testing have been made since the introduction of PCR, although new technologies are being investigated. Many tests that form the backbone of the “modern” microbiology laboratory are based on very old and labour-intensive technologies such as microscopy for malaria. Pressing needs include more rapid tests without sacrificing sensitivity, value-added tests, and point-of-care tests for both high- and low-resource settings. In recent years, research has been focused on alternative methods to improve the diagnosis of parasitic diseases. These include immunoassays, molecular-based approaches, and proteomics using mass spectrometry platforms technology. This review summarizes the progress in new approaches in parasite diagnosis and discusses some of the merits and disadvantages of these tests. |
| format | Article |
| id | doaj-art-041fd3c9ead14147bcfa314bfe446e9b |
| institution | Kabale University |
| issn | 1687-708X 1687-7098 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Interdisciplinary Perspectives on Infectious Diseases |
| spelling | doaj-art-041fd3c9ead14147bcfa314bfe446e9b2025-02-03T01:31:36ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982009-01-01200910.1155/2009/278246278246Diagnosis of Parasitic Diseases: Old and New ApproachesMomar Ndao0National Reference Centre for Parasitology, McGill University Centre for Tropical Diseases, Montreal General Hospital, 1650 Cedar Avenue R3-137, Montreal, QC, H3G 1A4, CanadaMethods for the diagnosis of infectious diseases have stagnated in the last 20–30 years. Few major advances in clinical diagnostic testing have been made since the introduction of PCR, although new technologies are being investigated. Many tests that form the backbone of the “modern” microbiology laboratory are based on very old and labour-intensive technologies such as microscopy for malaria. Pressing needs include more rapid tests without sacrificing sensitivity, value-added tests, and point-of-care tests for both high- and low-resource settings. In recent years, research has been focused on alternative methods to improve the diagnosis of parasitic diseases. These include immunoassays, molecular-based approaches, and proteomics using mass spectrometry platforms technology. This review summarizes the progress in new approaches in parasite diagnosis and discusses some of the merits and disadvantages of these tests.http://dx.doi.org/10.1155/2009/278246 |
| spellingShingle | Momar Ndao Diagnosis of Parasitic Diseases: Old and New Approaches Interdisciplinary Perspectives on Infectious Diseases |
| title | Diagnosis of Parasitic Diseases: Old and New Approaches |
| title_full | Diagnosis of Parasitic Diseases: Old and New Approaches |
| title_fullStr | Diagnosis of Parasitic Diseases: Old and New Approaches |
| title_full_unstemmed | Diagnosis of Parasitic Diseases: Old and New Approaches |
| title_short | Diagnosis of Parasitic Diseases: Old and New Approaches |
| title_sort | diagnosis of parasitic diseases old and new approaches |
| url | http://dx.doi.org/10.1155/2009/278246 |
| work_keys_str_mv | AT momarndao diagnosisofparasiticdiseasesoldandnewapproaches |