Green Synthesis of Copper Nanoparticles from the Aqueous Extract of <i>Lonicera japonica</i> Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity
In this study, copper nanoparticles with an average particle size of 2–4 nm were synthesized using the green extract of <i>Lonicera japonica</i> Thunb. The catalytic activity and dye degradation efficiency of Cu NPs were evaluated using ultraviolet spectroscopy. To confirm that Cu NPs ca...
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2025-01-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/15/2/91 |
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| author | Weijie Yu Jingyi Tang Chunxia Gao Xuesong Zheng Peizhi Zhu |
| author_facet | Weijie Yu Jingyi Tang Chunxia Gao Xuesong Zheng Peizhi Zhu |
| author_sort | Weijie Yu |
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| description | In this study, copper nanoparticles with an average particle size of 2–4 nm were synthesized using the green extract of <i>Lonicera japonica</i> Thunb. The catalytic activity and dye degradation efficiency of Cu NPs were evaluated using ultraviolet spectroscopy. To confirm that Cu NPs can continuously remove organic dyes, this study used Cu/Lj-C composite material adsorbed on cotton balls as a simulated bed to study the cyclic catalytic activity of Cu NPs for the reduction of methylene blue by sodium borohydride (NaBH<sub>4</sub>). The experiment showed that after multiple cycles, it can also quickly and effectively reduce methylene blue. To evaluate the toxicity of Cu NPs, experiments were conducted using HUVEC and MC3T3-E1 cells. The median lethal doses (LD<sub>50</sub>) were 37.64 µg/mL and 7.50 µg/mL. The synthesized Cu NPs also exhibited antibacterial efficacy against <i>Aspergillus niger</i> (fungus), <i>Staphylococcus aureus</i> (Gram-positive bacteria), <i>Escherichia coli</i> (Gram-negative bacteria), and <i>Candida albicans</i> (yeast). |
| format | Article |
| id | doaj-art-040aa18b5e7d4c38a755dc84f6c2765e |
| institution | Kabale University |
| issn | 2079-4991 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj-art-040aa18b5e7d4c38a755dc84f6c2765e2025-01-24T13:44:06ZengMDPI AGNanomaterials2079-49912025-01-011529110.3390/nano15020091Green Synthesis of Copper Nanoparticles from the Aqueous Extract of <i>Lonicera japonica</i> Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial ActivityWeijie Yu0Jingyi Tang1Chunxia Gao2Xuesong Zheng3Peizhi Zhu4School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, ChinaSchool of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, ChinaSchool of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, ChinaSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 201418, ChinaSchool of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, ChinaIn this study, copper nanoparticles with an average particle size of 2–4 nm were synthesized using the green extract of <i>Lonicera japonica</i> Thunb. The catalytic activity and dye degradation efficiency of Cu NPs were evaluated using ultraviolet spectroscopy. To confirm that Cu NPs can continuously remove organic dyes, this study used Cu/Lj-C composite material adsorbed on cotton balls as a simulated bed to study the cyclic catalytic activity of Cu NPs for the reduction of methylene blue by sodium borohydride (NaBH<sub>4</sub>). The experiment showed that after multiple cycles, it can also quickly and effectively reduce methylene blue. To evaluate the toxicity of Cu NPs, experiments were conducted using HUVEC and MC3T3-E1 cells. The median lethal doses (LD<sub>50</sub>) were 37.64 µg/mL and 7.50 µg/mL. The synthesized Cu NPs also exhibited antibacterial efficacy against <i>Aspergillus niger</i> (fungus), <i>Staphylococcus aureus</i> (Gram-positive bacteria), <i>Escherichia coli</i> (Gram-negative bacteria), and <i>Candida albicans</i> (yeast).https://www.mdpi.com/2079-4991/15/2/91green synthesis<i>Lonicera japonica</i> ThunbCu NPsdyes reductioncytotoxicityantibacterial |
| spellingShingle | Weijie Yu Jingyi Tang Chunxia Gao Xuesong Zheng Peizhi Zhu Green Synthesis of Copper Nanoparticles from the Aqueous Extract of <i>Lonicera japonica</i> Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity Nanomaterials green synthesis <i>Lonicera japonica</i> Thunb Cu NPs dyes reduction cytotoxicity antibacterial |
| title | Green Synthesis of Copper Nanoparticles from the Aqueous Extract of <i>Lonicera japonica</i> Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity |
| title_full | Green Synthesis of Copper Nanoparticles from the Aqueous Extract of <i>Lonicera japonica</i> Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity |
| title_fullStr | Green Synthesis of Copper Nanoparticles from the Aqueous Extract of <i>Lonicera japonica</i> Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity |
| title_full_unstemmed | Green Synthesis of Copper Nanoparticles from the Aqueous Extract of <i>Lonicera japonica</i> Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity |
| title_short | Green Synthesis of Copper Nanoparticles from the Aqueous Extract of <i>Lonicera japonica</i> Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity |
| title_sort | green synthesis of copper nanoparticles from the aqueous extract of i lonicera japonica i thunb and evaluation of its catalytic property and cytotoxicity and antimicrobial activity |
| topic | green synthesis <i>Lonicera japonica</i> Thunb Cu NPs dyes reduction cytotoxicity antibacterial |
| url | https://www.mdpi.com/2079-4991/15/2/91 |
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