Evolution of Choroidal Neovascularization due to Presumed Ocular Histoplasmosis Syndrome on Multimodal Imaging including Optical Coherence Tomography Angiography
A 37-year-old Caucasian woman presented with acute decrease in central vision in her right eye and was found to have subfoveal choroidal neovascularization (CNV) due to presumed ocular histoplasmosis syndrome (POHS). Her visual acuity improved from 20/70 to 20/20 at her 6-month follow-up, after 3 co...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/4098419 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832553376507756544 |
|---|---|
| author | T. Y. Alvin Liu Alice Yang Zhang Adam Wenick |
| author_facet | T. Y. Alvin Liu Alice Yang Zhang Adam Wenick |
| author_sort | T. Y. Alvin Liu |
| collection | DOAJ |
| description | A 37-year-old Caucasian woman presented with acute decrease in central vision in her right eye and was found to have subfoveal choroidal neovascularization (CNV) due to presumed ocular histoplasmosis syndrome (POHS). Her visual acuity improved from 20/70 to 20/20 at her 6-month follow-up, after 3 consecutive monthly intravitreal bevacizumab injections were initiated at her first visit. Although no CNV activity was seen on fluorescein angiography (FA) or spectral-domain optical coherence tomography (SD-OCT) at her 2-month, 4-month, and 6-month follow-up visits, persistent flow in the CNV lesion was detected on optical coherence tomography angiography (OCTA). OCTA shows persistent vascular flow as well as changes in vascular flow in CNV lesions associated with POHS, indicating the continued presence of patent vessels and changes in these CNV lesions, even when traditional imaging of the lesion with OCT and FA indicates stability of the lesion with no disease activity. Additional cases with longitudinal follow-up are needed to assess how OCTA should be incorporated into clinical practice. |
| format | Article |
| id | doaj-art-0405f67ba95c45408a3f900d5bbe1a72 |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-0405f67ba95c45408a3f900d5bbe1a722025-02-03T05:54:04ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302018-01-01201810.1155/2018/40984194098419Evolution of Choroidal Neovascularization due to Presumed Ocular Histoplasmosis Syndrome on Multimodal Imaging including Optical Coherence Tomography AngiographyT. Y. Alvin Liu0Alice Yang Zhang1Adam Wenick2Retina Division, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USARetina Division, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USARetina Division, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAA 37-year-old Caucasian woman presented with acute decrease in central vision in her right eye and was found to have subfoveal choroidal neovascularization (CNV) due to presumed ocular histoplasmosis syndrome (POHS). Her visual acuity improved from 20/70 to 20/20 at her 6-month follow-up, after 3 consecutive monthly intravitreal bevacizumab injections were initiated at her first visit. Although no CNV activity was seen on fluorescein angiography (FA) or spectral-domain optical coherence tomography (SD-OCT) at her 2-month, 4-month, and 6-month follow-up visits, persistent flow in the CNV lesion was detected on optical coherence tomography angiography (OCTA). OCTA shows persistent vascular flow as well as changes in vascular flow in CNV lesions associated with POHS, indicating the continued presence of patent vessels and changes in these CNV lesions, even when traditional imaging of the lesion with OCT and FA indicates stability of the lesion with no disease activity. Additional cases with longitudinal follow-up are needed to assess how OCTA should be incorporated into clinical practice.http://dx.doi.org/10.1155/2018/4098419 |
| spellingShingle | T. Y. Alvin Liu Alice Yang Zhang Adam Wenick Evolution of Choroidal Neovascularization due to Presumed Ocular Histoplasmosis Syndrome on Multimodal Imaging including Optical Coherence Tomography Angiography Case Reports in Ophthalmological Medicine |
| title | Evolution of Choroidal Neovascularization due to Presumed Ocular Histoplasmosis Syndrome on Multimodal Imaging including Optical Coherence Tomography Angiography |
| title_full | Evolution of Choroidal Neovascularization due to Presumed Ocular Histoplasmosis Syndrome on Multimodal Imaging including Optical Coherence Tomography Angiography |
| title_fullStr | Evolution of Choroidal Neovascularization due to Presumed Ocular Histoplasmosis Syndrome on Multimodal Imaging including Optical Coherence Tomography Angiography |
| title_full_unstemmed | Evolution of Choroidal Neovascularization due to Presumed Ocular Histoplasmosis Syndrome on Multimodal Imaging including Optical Coherence Tomography Angiography |
| title_short | Evolution of Choroidal Neovascularization due to Presumed Ocular Histoplasmosis Syndrome on Multimodal Imaging including Optical Coherence Tomography Angiography |
| title_sort | evolution of choroidal neovascularization due to presumed ocular histoplasmosis syndrome on multimodal imaging including optical coherence tomography angiography |
| url | http://dx.doi.org/10.1155/2018/4098419 |
| work_keys_str_mv | AT tyalvinliu evolutionofchoroidalneovascularizationduetopresumedocularhistoplasmosissyndromeonmultimodalimagingincludingopticalcoherencetomographyangiography AT aliceyangzhang evolutionofchoroidalneovascularizationduetopresumedocularhistoplasmosissyndromeonmultimodalimagingincludingopticalcoherencetomographyangiography AT adamwenick evolutionofchoroidalneovascularizationduetopresumedocularhistoplasmosissyndromeonmultimodalimagingincludingopticalcoherencetomographyangiography |