Reverse vaccinology-based multi-epitope COVID-19 vaccine targeting SARS-CoV-2 structural and non-structural proteins induces immune responses in mice

Reverse vaccinology-based multi-epitope COVID-19 vaccine targeting SARS-CoV-2 structural and non-structural proteins induces immune responses in mice

Vaccination is effective to end pandemics, including the Coronavirus disease-2019 (COVID-19). However, the evolution of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) which is characterized by the emergence of the virus variants has a great potential to cause a decrease in the effectiv...

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Bibliographic Details
Main Authors: Azzania Fibriani, Nicholas Yamahoki, Annisa Meliana Shani, Afifatur Rofiqoh, Agust Leo Fany Siregar, Cynthia Gunawan, Carola Giovanni Danira Mayorga, Tommy Octavianus Soetrisno Tjia, Husna Nugrahapraja, Ernawati Arifin Giri-Rachman, Marselina Irasonia Tan
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Vaccine: X
Subjects:
SARS-CoV-2
Recombinant vaccine
Peptide-based vaccine
Multi-epitope vaccine
Reverse vaccinology
Immunogenicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2590136225000269
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