Carcinosarcoma of the Gallbladder with Chondrosarcomatous Differentiation and Intracytoplasmic Eosinophilic Hyaline Globules (Thanatosomes): A Report of a Case and Review of the Literature
A 52-year-old woman presented with abdominal pain and vomiting. Computed tomography (CT) scan of the abdomen revealed a huge exophytic gallbladder mass displacing or invading the surrounding structures. The patient underwent radical cholecystectomy, transverse colectomy, distal gastrectomy, and live...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2019/9697235 |
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| author | Jumana A. Alratroot Amani A. Joudeh Samir S. Amr |
| author_facet | Jumana A. Alratroot Amani A. Joudeh Samir S. Amr |
| author_sort | Jumana A. Alratroot |
| collection | DOAJ |
| description | A 52-year-old woman presented with abdominal pain and vomiting. Computed tomography (CT) scan of the abdomen revealed a huge exophytic gallbladder mass displacing or invading the surrounding structures. The patient underwent radical cholecystectomy, transverse colectomy, distal gastrectomy, and liver bed resection. Histologically, the tumor showed both carcinomatous and sarcomatous components, with prominent chondrosarcomatous differentiation. In addition, several malignant cells showed intracytoplasmic eosinophilic hyaline globules (Thanatosomes). The tumor showed metastatic deposits to the omentum, the liver, and the peripancreatic lymph nodes. We report this unusual case and present a review of all cases of carcinosarcoma of the gallbladder with chondrosarcomatous differentiation. |
| format | Article |
| id | doaj-art-03ea0c92c7e843e8adb0e157f472f420 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-03ea0c92c7e843e8adb0e157f472f4202025-02-03T01:02:49ZengWileyCase Reports in Pathology2090-67812090-679X2019-01-01201910.1155/2019/96972359697235Carcinosarcoma of the Gallbladder with Chondrosarcomatous Differentiation and Intracytoplasmic Eosinophilic Hyaline Globules (Thanatosomes): A Report of a Case and Review of the LiteratureJumana A. Alratroot0Amani A. Joudeh1Samir S. Amr2Department of Pathology, Faculty of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaDepartment of Pathology and Laboratory Medicine, King Fahad Specialist Hospital, Amer Bin Thabet Street, Dammam 31444, Saudi ArabiaDepartment of Pathology and Laboratory Medicine, King Fahad Specialist Hospital, Amer Bin Thabet Street, Dammam 31444, Saudi ArabiaA 52-year-old woman presented with abdominal pain and vomiting. Computed tomography (CT) scan of the abdomen revealed a huge exophytic gallbladder mass displacing or invading the surrounding structures. The patient underwent radical cholecystectomy, transverse colectomy, distal gastrectomy, and liver bed resection. Histologically, the tumor showed both carcinomatous and sarcomatous components, with prominent chondrosarcomatous differentiation. In addition, several malignant cells showed intracytoplasmic eosinophilic hyaline globules (Thanatosomes). The tumor showed metastatic deposits to the omentum, the liver, and the peripancreatic lymph nodes. We report this unusual case and present a review of all cases of carcinosarcoma of the gallbladder with chondrosarcomatous differentiation.http://dx.doi.org/10.1155/2019/9697235 |
| spellingShingle | Jumana A. Alratroot Amani A. Joudeh Samir S. Amr Carcinosarcoma of the Gallbladder with Chondrosarcomatous Differentiation and Intracytoplasmic Eosinophilic Hyaline Globules (Thanatosomes): A Report of a Case and Review of the Literature Case Reports in Pathology |
| title | Carcinosarcoma of the Gallbladder with Chondrosarcomatous Differentiation and Intracytoplasmic Eosinophilic Hyaline Globules (Thanatosomes): A Report of a Case and Review of the Literature |
| title_full | Carcinosarcoma of the Gallbladder with Chondrosarcomatous Differentiation and Intracytoplasmic Eosinophilic Hyaline Globules (Thanatosomes): A Report of a Case and Review of the Literature |
| title_fullStr | Carcinosarcoma of the Gallbladder with Chondrosarcomatous Differentiation and Intracytoplasmic Eosinophilic Hyaline Globules (Thanatosomes): A Report of a Case and Review of the Literature |
| title_full_unstemmed | Carcinosarcoma of the Gallbladder with Chondrosarcomatous Differentiation and Intracytoplasmic Eosinophilic Hyaline Globules (Thanatosomes): A Report of a Case and Review of the Literature |
| title_short | Carcinosarcoma of the Gallbladder with Chondrosarcomatous Differentiation and Intracytoplasmic Eosinophilic Hyaline Globules (Thanatosomes): A Report of a Case and Review of the Literature |
| title_sort | carcinosarcoma of the gallbladder with chondrosarcomatous differentiation and intracytoplasmic eosinophilic hyaline globules thanatosomes a report of a case and review of the literature |
| url | http://dx.doi.org/10.1155/2019/9697235 |
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