A combination of four Toxoplasma gondii nuclear-targeted effectors protects against interferon gamma-driven human host cell death
ABSTRACT In both mice and humans, Type II interferon gamma (IFNγ) is crucial for the regulation of Toxoplasma gondii (T. gondii) infection, during acute or chronic phases. To thwart this defense, T. gondii secretes protein effectors hindering the host’s immune response. For example, T. gondii relies...
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| Main Authors: | Brittany Henry, Aubrey J. Phillips, L. David Sibley, Alex Rosenberg |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2024-10-01
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| Series: | mBio |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/mbio.02124-24 |
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