Radiation-Induced Sarcoma following Prolonged Coronary Stent Placement

Radiation exposure for the average coronary stent placement varies based on a number of factors but typically amounts to 6–11 mSv per patient (compared to 3 mSv background). As with all procedures which utilize radiation, there is an inherent risk of genetic mutation and the possible development of...

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Main Authors: Eric J. Vick, Christopher T. Clark, James M. Lewis
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2018/2903801
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author Eric J. Vick
Christopher T. Clark
James M. Lewis
author_facet Eric J. Vick
Christopher T. Clark
James M. Lewis
author_sort Eric J. Vick
collection DOAJ
description Radiation exposure for the average coronary stent placement varies based on a number of factors but typically amounts to 6–11 mSv per patient (compared to 3 mSv background). As with all procedures which utilize radiation, there is an inherent risk of genetic mutation and the possible development of malignancy. Here, we present the case of a 75-year-old male who presented with an exophytic mass on his back following prolonged coronary catheterization with a radiation burn seven years prior. Biopsy of the lesion revealed the mass was consistent with an undifferentiated pleomorphic sarcoma emanating from the site of the radiation burn. After staging studies demonstrated no evidence of metastatic disease, radical excision with negative margins was performed. This case demonstrates that despite the rarity of radiation injury, each incidence necessitates strict monitoring of radiation exposure and continual follow-up due to the risk of malignancy.
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spelling doaj-art-03de7a4f5cd64acc8dd406a1714b3c492025-02-03T07:24:42ZengWileyCase Reports in Surgery2090-69002090-69192018-01-01201810.1155/2018/29038012903801Radiation-Induced Sarcoma following Prolonged Coronary Stent PlacementEric J. Vick0Christopher T. Clark1James M. Lewis2College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, USADepartment of Pathology, University of Tennessee Medical Center, Knoxville, TN, USADepartment of Surgical Oncology, University of Tennessee Medical Center, Knoxville, TN, USARadiation exposure for the average coronary stent placement varies based on a number of factors but typically amounts to 6–11 mSv per patient (compared to 3 mSv background). As with all procedures which utilize radiation, there is an inherent risk of genetic mutation and the possible development of malignancy. Here, we present the case of a 75-year-old male who presented with an exophytic mass on his back following prolonged coronary catheterization with a radiation burn seven years prior. Biopsy of the lesion revealed the mass was consistent with an undifferentiated pleomorphic sarcoma emanating from the site of the radiation burn. After staging studies demonstrated no evidence of metastatic disease, radical excision with negative margins was performed. This case demonstrates that despite the rarity of radiation injury, each incidence necessitates strict monitoring of radiation exposure and continual follow-up due to the risk of malignancy.http://dx.doi.org/10.1155/2018/2903801
spellingShingle Eric J. Vick
Christopher T. Clark
James M. Lewis
Radiation-Induced Sarcoma following Prolonged Coronary Stent Placement
Case Reports in Surgery
title Radiation-Induced Sarcoma following Prolonged Coronary Stent Placement
title_full Radiation-Induced Sarcoma following Prolonged Coronary Stent Placement
title_fullStr Radiation-Induced Sarcoma following Prolonged Coronary Stent Placement
title_full_unstemmed Radiation-Induced Sarcoma following Prolonged Coronary Stent Placement
title_short Radiation-Induced Sarcoma following Prolonged Coronary Stent Placement
title_sort radiation induced sarcoma following prolonged coronary stent placement
url http://dx.doi.org/10.1155/2018/2903801
work_keys_str_mv AT ericjvick radiationinducedsarcomafollowingprolongedcoronarystentplacement
AT christophertclark radiationinducedsarcomafollowingprolongedcoronarystentplacement
AT jamesmlewis radiationinducedsarcomafollowingprolongedcoronarystentplacement