The Effect of Physical Activity agains the Telomere Length in the Leukocytes Cells of KONI Athletes

<p class="IsiAbstrakIndo">Telomeres are strands of non coding DNA at the ends of chromosomes that have the primary function to protect DNA from damage and maintain chromosomal stability. Physical exercise will increase the antioxidant activity can increase telomere proteins, lengthen...

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Main Authors: Endang Purwaningsih, Titiek Djannatun, Etty Widayanti, Yulia Suciati, Yenni Zulhamidah
Format: Article
Language:English
Published: Universitas Negeri Semarang 2017-07-01
Series:Biosaintifika: Journal of Biology & Biology Education
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Online Access:https://journal.unnes.ac.id/nju/index.php/biosaintifika/article/view/6207
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author Endang Purwaningsih
Titiek Djannatun
Etty Widayanti
Yulia Suciati
Yenni Zulhamidah
author_facet Endang Purwaningsih
Titiek Djannatun
Etty Widayanti
Yulia Suciati
Yenni Zulhamidah
author_sort Endang Purwaningsih
collection DOAJ
description <p class="IsiAbstrakIndo">Telomeres are strands of non coding DNA at the ends of chromosomes that have the primary function to protect DNA from damage and maintain chromosomal stability. Physical exercise will increase the antioxidant activity can increase telomere proteins, lengthen telomeres and or protein networks associated with telomere so that the telomere remains long, or stopping telomere shortening. Telomere length was also associated with age. The purpose of the research was to determine telomere length of leukocyte cells in the KONI (Indonesian National Sports Committee) athletes in Jakarta. The research method is descriptive, by measuring telomere length using quantitative PCR on leukocyte cells. Samples are KONI athletes from several sports, including men and women athletes, with ages between 15-20 years. Used a control group (not athletes) is students of the Faculty of Medicine, University of YARSI. The results showed that there was no significant difference (p&gt; 0.05) between telomere length group of athletes with the control group in both sexes. Similarly, telomere length between athlete male with female athletes also showed no significant difference (p&gt; 0.05). It was concluded that physical exercise in athletes KONI at the age of 15- 20 years had no effect on telomere length in leukocytes. The results of this study provide information about the telomere length in Indonesian athletes at an early age.</p>
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issn 2085-191X
2338-7610
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publisher Universitas Negeri Semarang
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spelling doaj-art-03c69ffa8f6a4034ab8edbbda9f9e99c2025-08-20T02:03:19ZengUniversitas Negeri SemarangBiosaintifika: Journal of Biology & Biology Education2085-191X2338-76102017-07-019222523210.15294/biosaintifika.v9i2.62076162The Effect of Physical Activity agains the Telomere Length in the Leukocytes Cells of KONI AthletesEndang Purwaningsih0Titiek Djannatun1Etty Widayanti2Yulia Suciati3Yenni Zulhamidah4Department Anatomy, Faculty of Medicine, YARSI University, JakartaDepartment Microbiology-Parasitology, Faculty of Medicine, YARSI University, JakartaDepartment Anatomy, Faculty of Medicine, YARSI University, JakartaDepartment Biochemistry, Faculty of Medicine, YARSI University, JakartaDepartment Anatomy, Faculty of Medicine, YARSI University, Jakarta<p class="IsiAbstrakIndo">Telomeres are strands of non coding DNA at the ends of chromosomes that have the primary function to protect DNA from damage and maintain chromosomal stability. Physical exercise will increase the antioxidant activity can increase telomere proteins, lengthen telomeres and or protein networks associated with telomere so that the telomere remains long, or stopping telomere shortening. Telomere length was also associated with age. The purpose of the research was to determine telomere length of leukocyte cells in the KONI (Indonesian National Sports Committee) athletes in Jakarta. The research method is descriptive, by measuring telomere length using quantitative PCR on leukocyte cells. Samples are KONI athletes from several sports, including men and women athletes, with ages between 15-20 years. Used a control group (not athletes) is students of the Faculty of Medicine, University of YARSI. The results showed that there was no significant difference (p&gt; 0.05) between telomere length group of athletes with the control group in both sexes. Similarly, telomere length between athlete male with female athletes also showed no significant difference (p&gt; 0.05). It was concluded that physical exercise in athletes KONI at the age of 15- 20 years had no effect on telomere length in leukocytes. The results of this study provide information about the telomere length in Indonesian athletes at an early age.</p>https://journal.unnes.ac.id/nju/index.php/biosaintifika/article/view/6207physical exercisetelomere lengthKONIqPCR
spellingShingle Endang Purwaningsih
Titiek Djannatun
Etty Widayanti
Yulia Suciati
Yenni Zulhamidah
The Effect of Physical Activity agains the Telomere Length in the Leukocytes Cells of KONI Athletes
Biosaintifika: Journal of Biology & Biology Education
physical exercise
telomere length
KONI
qPCR
title The Effect of Physical Activity agains the Telomere Length in the Leukocytes Cells of KONI Athletes
title_full The Effect of Physical Activity agains the Telomere Length in the Leukocytes Cells of KONI Athletes
title_fullStr The Effect of Physical Activity agains the Telomere Length in the Leukocytes Cells of KONI Athletes
title_full_unstemmed The Effect of Physical Activity agains the Telomere Length in the Leukocytes Cells of KONI Athletes
title_short The Effect of Physical Activity agains the Telomere Length in the Leukocytes Cells of KONI Athletes
title_sort effect of physical activity agains the telomere length in the leukocytes cells of koni athletes
topic physical exercise
telomere length
KONI
qPCR
url https://journal.unnes.ac.id/nju/index.php/biosaintifika/article/view/6207
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