Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema

Hereditary angioedema (HAE) is an autosomal dominantly inherited disease caused by deficiency of C1 esterase inhibitor protein type 1 (about 85% of patients with HAE-C1-INH) or type 2 oedema (about 15% of patients with HAE-C1-INH) by C1 inhibitor dysfunction, with normal serum levels (HAE-2). Long-t...

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Main Authors: Artur Gęsicki, Maciej F. Kozlowski, Karolina Żurawska, Weronika Ossowska, Jakub Sikora, Szymon Dyguś, Iwona Poziomkowska-Gęsicka
Format: Article
Language:English
Published: Termedia Publishing House 2024-08-01
Series:Alergologia Polska
Subjects:
Online Access:https://www.termedia.pl/Personalized-biological-treatment-with-lanadelumab-in-a-patient-with-recurrent-attacks-of-hereditary-angioedema,123,54687,1,1.html
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author Artur Gęsicki
Maciej F. Kozlowski
Karolina Żurawska
Weronika Ossowska
Jakub Sikora
Szymon Dyguś
Iwona Poziomkowska-Gęsicka
author_facet Artur Gęsicki
Maciej F. Kozlowski
Karolina Żurawska
Weronika Ossowska
Jakub Sikora
Szymon Dyguś
Iwona Poziomkowska-Gęsicka
author_sort Artur Gęsicki
collection DOAJ
description Hereditary angioedema (HAE) is an autosomal dominantly inherited disease caused by deficiency of C1 esterase inhibitor protein type 1 (about 85% of patients with HAE-C1-INH) or type 2 oedema (about 15% of patients with HAE-C1-INH) by C1 inhibitor dysfunction, with normal serum levels (HAE-2). Long-term treatment to prevent further attacks consists of continuous and regular administration of medications to reduce the number and severity of oedema attacks in HAE patients, thereby reducing the indirect burden of the disease. With the severe course of the disease, potentially life-threatening during flare-ups, it is expedient to implement long-term HAE attacks prophylaxis, which was very limited in Poland until September 2021.
format Article
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institution Kabale University
issn 2353-3854
2391-6052
language English
publishDate 2024-08-01
publisher Termedia Publishing House
record_format Article
series Alergologia Polska
spelling doaj-art-0395dcecf2624986871e54f753c566f82025-01-27T10:35:03ZengTermedia Publishing HouseAlergologia Polska2353-38542391-60522024-08-0111433233410.5114/pja.2024.14260254687Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedemaArtur GęsickiMaciej F. KozlowskiKarolina ŻurawskaWeronika OssowskaJakub SikoraSzymon DyguśIwona Poziomkowska-GęsickaHereditary angioedema (HAE) is an autosomal dominantly inherited disease caused by deficiency of C1 esterase inhibitor protein type 1 (about 85% of patients with HAE-C1-INH) or type 2 oedema (about 15% of patients with HAE-C1-INH) by C1 inhibitor dysfunction, with normal serum levels (HAE-2). Long-term treatment to prevent further attacks consists of continuous and regular administration of medications to reduce the number and severity of oedema attacks in HAE patients, thereby reducing the indirect burden of the disease. With the severe course of the disease, potentially life-threatening during flare-ups, it is expedient to implement long-term HAE attacks prophylaxis, which was very limited in Poland until September 2021.https://www.termedia.pl/Personalized-biological-treatment-with-lanadelumab-in-a-patient-with-recurrent-attacks-of-hereditary-angioedema,123,54687,1,1.htmlcongenital angioedema hereditary angioedema lanadelumab hereditary angioedema biological treatment
spellingShingle Artur Gęsicki
Maciej F. Kozlowski
Karolina Żurawska
Weronika Ossowska
Jakub Sikora
Szymon Dyguś
Iwona Poziomkowska-Gęsicka
Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema
Alergologia Polska
congenital angioedema
hereditary angioedema
lanadelumab
hereditary angioedema
biological treatment
title Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema
title_full Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema
title_fullStr Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema
title_full_unstemmed Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema
title_short Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema
title_sort personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema
topic congenital angioedema
hereditary angioedema
lanadelumab
hereditary angioedema
biological treatment
url https://www.termedia.pl/Personalized-biological-treatment-with-lanadelumab-in-a-patient-with-recurrent-attacks-of-hereditary-angioedema,123,54687,1,1.html
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