Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema
Hereditary angioedema (HAE) is an autosomal dominantly inherited disease caused by deficiency of C1 esterase inhibitor protein type 1 (about 85% of patients with HAE-C1-INH) or type 2 oedema (about 15% of patients with HAE-C1-INH) by C1 inhibitor dysfunction, with normal serum levels (HAE-2). Long-t...
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Format: | Article |
Language: | English |
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Termedia Publishing House
2024-08-01
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Series: | Alergologia Polska |
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Online Access: | https://www.termedia.pl/Personalized-biological-treatment-with-lanadelumab-in-a-patient-with-recurrent-attacks-of-hereditary-angioedema,123,54687,1,1.html |
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author | Artur Gęsicki Maciej F. Kozlowski Karolina Żurawska Weronika Ossowska Jakub Sikora Szymon Dyguś Iwona Poziomkowska-Gęsicka |
author_facet | Artur Gęsicki Maciej F. Kozlowski Karolina Żurawska Weronika Ossowska Jakub Sikora Szymon Dyguś Iwona Poziomkowska-Gęsicka |
author_sort | Artur Gęsicki |
collection | DOAJ |
description | Hereditary angioedema (HAE) is an autosomal dominantly inherited disease caused by deficiency of C1 esterase inhibitor protein type 1 (about 85% of patients with HAE-C1-INH) or type 2 oedema (about 15% of patients with HAE-C1-INH) by C1 inhibitor dysfunction, with normal serum levels (HAE-2). Long-term treatment to prevent further attacks consists of continuous and regular administration of medications to reduce the number and severity of oedema attacks in HAE patients, thereby reducing the indirect burden of the disease. With the severe course of the disease, potentially life-threatening during flare-ups, it is expedient to implement long-term HAE attacks prophylaxis, which was very limited in Poland until September 2021. |
format | Article |
id | doaj-art-0395dcecf2624986871e54f753c566f8 |
institution | Kabale University |
issn | 2353-3854 2391-6052 |
language | English |
publishDate | 2024-08-01 |
publisher | Termedia Publishing House |
record_format | Article |
series | Alergologia Polska |
spelling | doaj-art-0395dcecf2624986871e54f753c566f82025-01-27T10:35:03ZengTermedia Publishing HouseAlergologia Polska2353-38542391-60522024-08-0111433233410.5114/pja.2024.14260254687Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedemaArtur GęsickiMaciej F. KozlowskiKarolina ŻurawskaWeronika OssowskaJakub SikoraSzymon DyguśIwona Poziomkowska-GęsickaHereditary angioedema (HAE) is an autosomal dominantly inherited disease caused by deficiency of C1 esterase inhibitor protein type 1 (about 85% of patients with HAE-C1-INH) or type 2 oedema (about 15% of patients with HAE-C1-INH) by C1 inhibitor dysfunction, with normal serum levels (HAE-2). Long-term treatment to prevent further attacks consists of continuous and regular administration of medications to reduce the number and severity of oedema attacks in HAE patients, thereby reducing the indirect burden of the disease. With the severe course of the disease, potentially life-threatening during flare-ups, it is expedient to implement long-term HAE attacks prophylaxis, which was very limited in Poland until September 2021.https://www.termedia.pl/Personalized-biological-treatment-with-lanadelumab-in-a-patient-with-recurrent-attacks-of-hereditary-angioedema,123,54687,1,1.htmlcongenital angioedema hereditary angioedema lanadelumab hereditary angioedema biological treatment |
spellingShingle | Artur Gęsicki Maciej F. Kozlowski Karolina Żurawska Weronika Ossowska Jakub Sikora Szymon Dyguś Iwona Poziomkowska-Gęsicka Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema Alergologia Polska congenital angioedema hereditary angioedema lanadelumab hereditary angioedema biological treatment |
title | Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema |
title_full | Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema |
title_fullStr | Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema |
title_full_unstemmed | Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema |
title_short | Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema |
title_sort | personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema |
topic | congenital angioedema hereditary angioedema lanadelumab hereditary angioedema biological treatment |
url | https://www.termedia.pl/Personalized-biological-treatment-with-lanadelumab-in-a-patient-with-recurrent-attacks-of-hereditary-angioedema,123,54687,1,1.html |
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