Incidence, Characteristics, and Management of Patients with Recurrent Myocardial Infarctions: Insights from the EYESHOT POST-MI

Background. It is unknown whether patients who survived two or multiple episodes of myocardial infarction (MI) present different clinical characteristics and management than patients at their first MI. Methods. The EYESHOT post-MI was a prospective, observational, nationwide study aimed to evaluate...

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Main Authors: Leonardo De Luca, Furio Colivicchi, Domenico Gabrielli, Donata Lucci, Gabriele Grippo, Francesco Piemonte, Bruno Villari, Andrea Di Lenarda, Fabrizio Oliva, Michele Massimo Gulizia
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Interventional Cardiology
Online Access:http://dx.doi.org/10.1155/2022/4593325
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author Leonardo De Luca
Furio Colivicchi
Domenico Gabrielli
Donata Lucci
Gabriele Grippo
Francesco Piemonte
Bruno Villari
Andrea Di Lenarda
Fabrizio Oliva
Michele Massimo Gulizia
author_facet Leonardo De Luca
Furio Colivicchi
Domenico Gabrielli
Donata Lucci
Gabriele Grippo
Francesco Piemonte
Bruno Villari
Andrea Di Lenarda
Fabrizio Oliva
Michele Massimo Gulizia
author_sort Leonardo De Luca
collection DOAJ
description Background. It is unknown whether patients who survived two or multiple episodes of myocardial infarction (MI) present different clinical characteristics and management than patients at their first MI. Methods. The EYESHOT post-MI was a prospective, observational, nationwide study aimed to evaluate the management of patients presenting to cardiologists 1 to 3 years from the last MI event. In 3 months of enrolment, 165 Italian cardiology centers included 1633 consecutive post-MI patients. In the present analysis, we stratified the study cohort according to the number of prior MI episodes (i.e., 1, 2 or ≥3). Results. Among the 1618 patients enrolled with complete data on MI history, 1335 (82.5%) were at their first MI episode, 209 (12.9%) had a history of 2 MIs, and the remaining 74 (4.6%) had ≥ 3 prior MIs. Patients with a history of multiple MIs were increasingly older and presented a significantly higher rate of risk factors compared to those at their first MI. During the year prior to enrolment, patients with 2 or ≥3 MI episodes more frequently underwent coronary angiography compared to the other group (p<0.0001). In addition, several lifesaving and antianginal drugs were more frequently prescribed in patients presenting with a history of multiple MIs compared to those at their first MI. Conclusions. Our data suggest that patients with multiple MIs managed by cardiologists in routine clinical practice present an incremental clinical risk, more frequently undergo coronary angiography, and are more intensively managed with pharmacological therapies compared to patients at their first MI episode.
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spelling doaj-art-039447dc9af94b79a8589c337ff0becc2025-02-03T01:10:36ZengWileyJournal of Interventional Cardiology1540-81832022-01-01202210.1155/2022/4593325Incidence, Characteristics, and Management of Patients with Recurrent Myocardial Infarctions: Insights from the EYESHOT POST-MILeonardo De Luca0Furio Colivicchi1Domenico Gabrielli2Donata Lucci3Gabriele Grippo4Francesco Piemonte5Bruno Villari6Andrea Di Lenarda7Fabrizio Oliva8Michele Massimo Gulizia9Department of CardiosciencesDivision of CardiologyDepartment of CardiosciencesANMCO Research CenterDivision of CardiologyDivision of CardiologyDivision of CardiologyDivision of CardiologyCardiac Intensive Care Unit and De Gasperis Cardio CenterDivision of CardiologyBackground. It is unknown whether patients who survived two or multiple episodes of myocardial infarction (MI) present different clinical characteristics and management than patients at their first MI. Methods. The EYESHOT post-MI was a prospective, observational, nationwide study aimed to evaluate the management of patients presenting to cardiologists 1 to 3 years from the last MI event. In 3 months of enrolment, 165 Italian cardiology centers included 1633 consecutive post-MI patients. In the present analysis, we stratified the study cohort according to the number of prior MI episodes (i.e., 1, 2 or ≥3). Results. Among the 1618 patients enrolled with complete data on MI history, 1335 (82.5%) were at their first MI episode, 209 (12.9%) had a history of 2 MIs, and the remaining 74 (4.6%) had ≥ 3 prior MIs. Patients with a history of multiple MIs were increasingly older and presented a significantly higher rate of risk factors compared to those at their first MI. During the year prior to enrolment, patients with 2 or ≥3 MI episodes more frequently underwent coronary angiography compared to the other group (p<0.0001). In addition, several lifesaving and antianginal drugs were more frequently prescribed in patients presenting with a history of multiple MIs compared to those at their first MI. Conclusions. Our data suggest that patients with multiple MIs managed by cardiologists in routine clinical practice present an incremental clinical risk, more frequently undergo coronary angiography, and are more intensively managed with pharmacological therapies compared to patients at their first MI episode.http://dx.doi.org/10.1155/2022/4593325
spellingShingle Leonardo De Luca
Furio Colivicchi
Domenico Gabrielli
Donata Lucci
Gabriele Grippo
Francesco Piemonte
Bruno Villari
Andrea Di Lenarda
Fabrizio Oliva
Michele Massimo Gulizia
Incidence, Characteristics, and Management of Patients with Recurrent Myocardial Infarctions: Insights from the EYESHOT POST-MI
Journal of Interventional Cardiology
title Incidence, Characteristics, and Management of Patients with Recurrent Myocardial Infarctions: Insights from the EYESHOT POST-MI
title_full Incidence, Characteristics, and Management of Patients with Recurrent Myocardial Infarctions: Insights from the EYESHOT POST-MI
title_fullStr Incidence, Characteristics, and Management of Patients with Recurrent Myocardial Infarctions: Insights from the EYESHOT POST-MI
title_full_unstemmed Incidence, Characteristics, and Management of Patients with Recurrent Myocardial Infarctions: Insights from the EYESHOT POST-MI
title_short Incidence, Characteristics, and Management of Patients with Recurrent Myocardial Infarctions: Insights from the EYESHOT POST-MI
title_sort incidence characteristics and management of patients with recurrent myocardial infarctions insights from the eyeshot post mi
url http://dx.doi.org/10.1155/2022/4593325
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