Plasma testosterone response at 1st and 4th day after short- and long-term hCG stimulation test
Human chorionic gonadotropin (hCG) stimulation test is a reliable dynamic test for the evaluation of testicular function during childhood. Several protocols have been recommended but their reliability is controversial. In order to decide the best timing to measure stimulated testosterone leve...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2004-10-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/2826 |
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| author | Pelin Adiyaman Gönül Ocal Merih Berberoğlu Zehra Aycan Olcay Evliyaoğlu Ergun Cetinkaya |
| author_facet | Pelin Adiyaman Gönül Ocal Merih Berberoğlu Zehra Aycan Olcay Evliyaoğlu Ergun Cetinkaya |
| author_sort | Pelin Adiyaman |
| collection | DOAJ |
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Human chorionic gonadotropin (hCG) stimulation test is a reliable dynamic test for the evaluation of testicular function during childhood. Several protocols have been recommended but their reliability is controversial. In order to decide the best timing to measure stimulated testosterone levels in short- and long-term hCG protocols, we evaluated 83 prepubertal patients in two group. In group A, 34 patients with isolated micropenis and in group B, 49 inguinal cryptorchidic patients were enrolled. In group A short-term hCG protocol (3000 IU/m2/im/3 days) and in group B long-term hCG protocol (1500 IU/m2/im; thrice a week for 3 weeks) was administered. Blood samples were drawn at the initiation of the test and then at the 1st and 4th days after the last hCG injection. Each case's peak stimulated testosterone (Tmax) and the incremenet in plasma testosterone (deltaT) were calculated and compared with the 1st and 4th day responses within the group. In the short-term protocol the 4th day responses were higher than the 1st day responses (p |
| format | Article |
| id | doaj-art-037859e85e424104bff8f3ae814fcccf |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2004-10-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-037859e85e424104bff8f3ae814fcccf2025-08-20T03:16:23ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212004-10-01464Plasma testosterone response at 1st and 4th day after short- and long-term hCG stimulation testPelin Adiyaman0Gönül OcalMerih BerberoğluZehra AycanOlcay EvliyaoğluErgun CetinkayaDepartment of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey. Human chorionic gonadotropin (hCG) stimulation test is a reliable dynamic test for the evaluation of testicular function during childhood. Several protocols have been recommended but their reliability is controversial. In order to decide the best timing to measure stimulated testosterone levels in short- and long-term hCG protocols, we evaluated 83 prepubertal patients in two group. In group A, 34 patients with isolated micropenis and in group B, 49 inguinal cryptorchidic patients were enrolled. In group A short-term hCG protocol (3000 IU/m2/im/3 days) and in group B long-term hCG protocol (1500 IU/m2/im; thrice a week for 3 weeks) was administered. Blood samples were drawn at the initiation of the test and then at the 1st and 4th days after the last hCG injection. Each case's peak stimulated testosterone (Tmax) and the incremenet in plasma testosterone (deltaT) were calculated and compared with the 1st and 4th day responses within the group. In the short-term protocol the 4th day responses were higher than the 1st day responses (phttps://turkjpediatr.org/article/view/2826 |
| spellingShingle | Pelin Adiyaman Gönül Ocal Merih Berberoğlu Zehra Aycan Olcay Evliyaoğlu Ergun Cetinkaya Plasma testosterone response at 1st and 4th day after short- and long-term hCG stimulation test The Turkish Journal of Pediatrics |
| title | Plasma testosterone response at 1st and 4th day after short- and long-term hCG stimulation test |
| title_full | Plasma testosterone response at 1st and 4th day after short- and long-term hCG stimulation test |
| title_fullStr | Plasma testosterone response at 1st and 4th day after short- and long-term hCG stimulation test |
| title_full_unstemmed | Plasma testosterone response at 1st and 4th day after short- and long-term hCG stimulation test |
| title_short | Plasma testosterone response at 1st and 4th day after short- and long-term hCG stimulation test |
| title_sort | plasma testosterone response at 1st and 4th day after short and long term hcg stimulation test |
| url | https://turkjpediatr.org/article/view/2826 |
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