Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive Strategies
Inflammatory bowel disease (IBD) refers to a group of chronic inflammatory diseases that targets mainly the gastrointestinal tract. The clinical presentation of IBD includes both gastrointestinal manifestations and extraintestinal manifestations (EIM). The reported cardiovascular manifestations in I...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2019/3012509 |
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| _version_ | 1832558771681886208 |
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| author | Diana-Maria Bunu Cristian-Eugen Timofte Manuela Ciocoiu Mariana Floria Claudia-Cristina Tarniceriu Oana-Bogdana Barboi Daniela-Maria Tanase |
| author_facet | Diana-Maria Bunu Cristian-Eugen Timofte Manuela Ciocoiu Mariana Floria Claudia-Cristina Tarniceriu Oana-Bogdana Barboi Daniela-Maria Tanase |
| author_sort | Diana-Maria Bunu |
| collection | DOAJ |
| description | Inflammatory bowel disease (IBD) refers to a group of chronic inflammatory diseases that targets mainly the gastrointestinal tract. The clinical presentation of IBD includes both gastrointestinal manifestations and extraintestinal manifestations (EIM). The reported cardiovascular manifestations in IBD patients include pericarditis, myocarditis, venous and arterial thromboembolism, arrhythmias, atrioventricular block, heart failure, endocarditis, valvulopathies, and Takayasu arteritis. The aim of this article is to review the available literature about the possible pathogenic mechanisms and determine preventive measures capable of reducing the incidence and severity of the cardiovascular manifestations. In IBD patients, the incidence of cardiovascular manifestations is low, but higher than that in the general population. Therefore, clinicians should pay attention to any new modification that might indicate cardiovascular involvement in IBD patients, and they should consider chronic inflammatory diseases in patients with cardiac conditions without an evident cause. Considering the role of inflammation in the development of cardiovascular manifestations, the management should include prevention of flares and maintenance of remission for as long as possible. Preventive measures should also include active screening and strict control of the cardiovascular risk factors in all IBD patients. |
| format | Article |
| id | doaj-art-0369ce0e96324c6382cdfc33828a96c5 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-0369ce0e96324c6382cdfc33828a96c52025-02-03T01:31:28ZengWileyGastroenterology Research and Practice1687-61211687-630X2019-01-01201910.1155/2019/30125093012509Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive StrategiesDiana-Maria Bunu0Cristian-Eugen Timofte1Manuela Ciocoiu2Mariana Floria3Claudia-Cristina Tarniceriu4Oana-Bogdana Barboi5Daniela-Maria Tanase6Department of Cardiology, Institute of Cardiovascular Diseases, Timisoara 300310, RomaniaDepartment of Radiology, County Emergency Hospital Timisoara, Timisoara 300723, RomaniaDepartment of Pathophysiology, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi 700111, RomaniaDepartment of Internal Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi 700111, RomaniaDepartment of Morpho-Functional Sciences I, Discipline of Anatomy, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi 700111, RomaniaInstitute of Gastroenterology and Hepatology-“Sf. Spiridon” County Clinical Emergency Hospital Iasi, Iasi, RomaniaDepartment of Internal Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi 700111, RomaniaInflammatory bowel disease (IBD) refers to a group of chronic inflammatory diseases that targets mainly the gastrointestinal tract. The clinical presentation of IBD includes both gastrointestinal manifestations and extraintestinal manifestations (EIM). The reported cardiovascular manifestations in IBD patients include pericarditis, myocarditis, venous and arterial thromboembolism, arrhythmias, atrioventricular block, heart failure, endocarditis, valvulopathies, and Takayasu arteritis. The aim of this article is to review the available literature about the possible pathogenic mechanisms and determine preventive measures capable of reducing the incidence and severity of the cardiovascular manifestations. In IBD patients, the incidence of cardiovascular manifestations is low, but higher than that in the general population. Therefore, clinicians should pay attention to any new modification that might indicate cardiovascular involvement in IBD patients, and they should consider chronic inflammatory diseases in patients with cardiac conditions without an evident cause. Considering the role of inflammation in the development of cardiovascular manifestations, the management should include prevention of flares and maintenance of remission for as long as possible. Preventive measures should also include active screening and strict control of the cardiovascular risk factors in all IBD patients.http://dx.doi.org/10.1155/2019/3012509 |
| spellingShingle | Diana-Maria Bunu Cristian-Eugen Timofte Manuela Ciocoiu Mariana Floria Claudia-Cristina Tarniceriu Oana-Bogdana Barboi Daniela-Maria Tanase Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive Strategies Gastroenterology Research and Practice |
| title | Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive Strategies |
| title_full | Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive Strategies |
| title_fullStr | Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive Strategies |
| title_full_unstemmed | Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive Strategies |
| title_short | Cardiovascular Manifestations of Inflammatory Bowel Disease: Pathogenesis, Diagnosis, and Preventive Strategies |
| title_sort | cardiovascular manifestations of inflammatory bowel disease pathogenesis diagnosis and preventive strategies |
| url | http://dx.doi.org/10.1155/2019/3012509 |
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