Multisite Kinetic Modeling of 13C Metabolic MR Using [1-13C]Pyruvate

Multisite Kinetic Modeling of 13C Metabolic MR Using [1-13C]Pyruvate

Hyperpolarized 13C imaging allows real-time in vivo measurements of metabolite levels. Quantification of metabolite conversion between [1-13C]pyruvate and downstream metabolites [1-13C]alanine, [1-13C]lactate, and [13C]bicarbonate can be achieved through kinetic modeling. Since pyruvate interacts dy...

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Bibliographic Details
Main Authors: Pedro A. Gómez Damián, Jonathan I. Sperl, Martin A. Janich, Oleksandr Khegai, Florian Wiesinger, Steffen J. Glaser, Axel Haase, Markus Schwaiger, Rolf F. Schulte, Marion I. Menzel
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Radiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2014/871619
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