Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy

Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy

The turnover of endoplasmic reticulum (ER) ensures the correct biological activity of its distinct domains. In mammalian cells, the ER is degraded via a selective autophagy pathway (ER-phagy), mediated by two specific receptors: FAM134B, responsible for the turnover of ER sheets and SEC62 that regul...

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Bibliographic Details
Main Authors: Paolo Grumati, Giulio Morozzi, Soraya Hölper, Muriel Mari, Marie-Lena IE Harwardt, Riqiang Yan, Stefan Müller, Fulvio Reggiori, Mike Heilemann, Ivan Dikic
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
selective autophagy
endoplasmic reticulum
RTN3
reticulon
autophagy
Online Access:https://elifesciences.org/articles/25555
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