Management for Patients with De Novo or Recurrent Tumors in the Residual Kidney after Surgery for Nonfamilial Bilateral Renal Cell Carcinoma
The tumor de novo in the residual kidney after surgery for nonfamilial bilateral renal cell carcinoma (RCC) is problematic. We reviewed 5 patients who experienced such a situation. Three patients had had metachronous bilateral RCC, treated with radical nephrectomy in one kidney and nephron-sparing s...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Advances in Urology |
| Online Access: | http://dx.doi.org/10.1155/2009/135143 |
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| author | Noboru Hara Tsutomu Nishiyama Norihiko Yoshimura Satoshi Takaki Kyoichiro Yamakado Yasuo Kitamura Kazuya Suzuki Kota Takahashi |
| author_facet | Noboru Hara Tsutomu Nishiyama Norihiko Yoshimura Satoshi Takaki Kyoichiro Yamakado Yasuo Kitamura Kazuya Suzuki Kota Takahashi |
| author_sort | Noboru Hara |
| collection | DOAJ |
| description | The tumor de novo in the residual kidney after surgery for nonfamilial bilateral renal cell carcinoma (RCC) is problematic. We reviewed 5 patients who experienced such a situation. Three patients had had metachronous bilateral RCC, treated with radical nephrectomy in one kidney and nephron-sparing surgery (NSS) in the other. Two patients had had synchronous disease; one patient had received radical nephrectomy and NSS, and the other bilateral NSS. The 5 patients had another solid mass/de novo tumor in the residual kidney 16–88 (mean 46.8) months after surgery. For the tumor de novo in earlier years (1992–1999), one patient underwent surgery and hemodialysis, and the other selected a conservative observation. In recent years (2000–2007), one patient was conservatively observed; the remaining 2 received computerized-tomography-guided radiofrequency ablation, and the local tumors were well controlled postoperatively for 20 and 12 months with their renal function unimpaired. Ablative techniques can potentially strike a balance between oncological and nephrological outcomes in patients with sporadic multiple RCC, successful management of which was difficult previously. |
| format | Article |
| id | doaj-art-0319e45083c34f9d8d943b7e0373b03c |
| institution | Kabale University |
| issn | 1687-6369 1687-6377 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Urology |
| spelling | doaj-art-0319e45083c34f9d8d943b7e0373b03c2025-02-03T05:59:24ZengWileyAdvances in Urology1687-63691687-63772009-01-01200910.1155/2009/135143135143Management for Patients with De Novo or Recurrent Tumors in the Residual Kidney after Surgery for Nonfamilial Bilateral Renal Cell CarcinomaNoboru Hara0Tsutomu Nishiyama1Norihiko Yoshimura2Satoshi Takaki3Kyoichiro Yamakado4Yasuo Kitamura5Kazuya Suzuki6Kota Takahashi7Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, JapanDivision of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, JapanDivision of Radiation Oncology, Department of Molecular Genetics, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, JapanDivision of Radiation Oncology, Department of Molecular Genetics, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, JapanDivision of Radiology, Mie University Graduate School of Medicine, Mie 514-8507, JapanDepartment of Urology, Niigata Cancer Center Hospital, Niigata 951-8566, JapanDivision of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, JapanDivision of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, JapanThe tumor de novo in the residual kidney after surgery for nonfamilial bilateral renal cell carcinoma (RCC) is problematic. We reviewed 5 patients who experienced such a situation. Three patients had had metachronous bilateral RCC, treated with radical nephrectomy in one kidney and nephron-sparing surgery (NSS) in the other. Two patients had had synchronous disease; one patient had received radical nephrectomy and NSS, and the other bilateral NSS. The 5 patients had another solid mass/de novo tumor in the residual kidney 16–88 (mean 46.8) months after surgery. For the tumor de novo in earlier years (1992–1999), one patient underwent surgery and hemodialysis, and the other selected a conservative observation. In recent years (2000–2007), one patient was conservatively observed; the remaining 2 received computerized-tomography-guided radiofrequency ablation, and the local tumors were well controlled postoperatively for 20 and 12 months with their renal function unimpaired. Ablative techniques can potentially strike a balance between oncological and nephrological outcomes in patients with sporadic multiple RCC, successful management of which was difficult previously.http://dx.doi.org/10.1155/2009/135143 |
| spellingShingle | Noboru Hara Tsutomu Nishiyama Norihiko Yoshimura Satoshi Takaki Kyoichiro Yamakado Yasuo Kitamura Kazuya Suzuki Kota Takahashi Management for Patients with De Novo or Recurrent Tumors in the Residual Kidney after Surgery for Nonfamilial Bilateral Renal Cell Carcinoma Advances in Urology |
| title | Management for Patients with De Novo or Recurrent Tumors in the Residual Kidney after Surgery for Nonfamilial Bilateral Renal Cell Carcinoma |
| title_full | Management for Patients with De Novo or Recurrent Tumors in the Residual Kidney after Surgery for Nonfamilial Bilateral Renal Cell Carcinoma |
| title_fullStr | Management for Patients with De Novo or Recurrent Tumors in the Residual Kidney after Surgery for Nonfamilial Bilateral Renal Cell Carcinoma |
| title_full_unstemmed | Management for Patients with De Novo or Recurrent Tumors in the Residual Kidney after Surgery for Nonfamilial Bilateral Renal Cell Carcinoma |
| title_short | Management for Patients with De Novo or Recurrent Tumors in the Residual Kidney after Surgery for Nonfamilial Bilateral Renal Cell Carcinoma |
| title_sort | management for patients with de novo or recurrent tumors in the residual kidney after surgery for nonfamilial bilateral renal cell carcinoma |
| url | http://dx.doi.org/10.1155/2009/135143 |
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