Global Distribution, Public Health and Clinical Impact of the Protozoan Pathogen Cryptosporidium
Cryptosporidium spp. are coccidians, oocysts-forming apicomplexan protozoa, which complete their life cycle both in humans and animals, through zoonotic and anthroponotic transmission, causing cryptosporidiosis. The global burden of this disease is still underascertained, due to a conundrum transmis...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Interdisciplinary Perspectives on Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2010/753512 |
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| author | Lorenza Putignani Donato Menichella |
| author_facet | Lorenza Putignani Donato Menichella |
| author_sort | Lorenza Putignani |
| collection | DOAJ |
| description | Cryptosporidium spp. are coccidians, oocysts-forming apicomplexan protozoa, which complete their life cycle both in humans and animals, through zoonotic and anthroponotic transmission, causing cryptosporidiosis. The global burden of this disease is still underascertained, due to a conundrum transmission modality, only partially unveiled, and on a plethora of detection systems still inadequate or only partially applied for worldwide surveillance. In children, cryptosporidiosis encumber is even less recorded and often misidentified due to physiological reasons such as early-age unpaired immunological response. Furthermore, malnutrition in underdeveloped countries or clinical underestimation of protozoan etiology in developed countries contribute to the underestimation of the worldwide burden. Principal key indicators of the parasite distribution were associated to environmental (e.g., geographic and temporal clusters, etc.) and host determinants of the infection (e.g., age, immunological status, travels, community behaviours). The distribution was geographically mapped to provide an updated picture of the global parasite ecosystems. The present paper aims to provide, by a critical analysis of existing literature, a link between observational epidemiological records and new insights on public health, and diagnostic and clinical impact of cryptosporidiosis. |
| format | Article |
| id | doaj-art-031193e02192442397b63157e060867a |
| institution | Kabale University |
| issn | 1687-708X 1687-7098 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Interdisciplinary Perspectives on Infectious Diseases |
| spelling | doaj-art-031193e02192442397b63157e060867a2025-02-03T06:06:36ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982010-01-01201010.1155/2010/753512753512Global Distribution, Public Health and Clinical Impact of the Protozoan Pathogen CryptosporidiumLorenza Putignani0Donato Menichella1Microbiology Unit, Bambino Gesù Pediatric Hospital, Scientific Institute, Piazza Sant'Onofrio 4, 00165 Rome, ItalyMicrobiology Unit, Bambino Gesù Pediatric Hospital, Scientific Institute, Piazza Sant'Onofrio 4, 00165 Rome, ItalyCryptosporidium spp. are coccidians, oocysts-forming apicomplexan protozoa, which complete their life cycle both in humans and animals, through zoonotic and anthroponotic transmission, causing cryptosporidiosis. The global burden of this disease is still underascertained, due to a conundrum transmission modality, only partially unveiled, and on a plethora of detection systems still inadequate or only partially applied for worldwide surveillance. In children, cryptosporidiosis encumber is even less recorded and often misidentified due to physiological reasons such as early-age unpaired immunological response. Furthermore, malnutrition in underdeveloped countries or clinical underestimation of protozoan etiology in developed countries contribute to the underestimation of the worldwide burden. Principal key indicators of the parasite distribution were associated to environmental (e.g., geographic and temporal clusters, etc.) and host determinants of the infection (e.g., age, immunological status, travels, community behaviours). The distribution was geographically mapped to provide an updated picture of the global parasite ecosystems. The present paper aims to provide, by a critical analysis of existing literature, a link between observational epidemiological records and new insights on public health, and diagnostic and clinical impact of cryptosporidiosis.http://dx.doi.org/10.1155/2010/753512 |
| spellingShingle | Lorenza Putignani Donato Menichella Global Distribution, Public Health and Clinical Impact of the Protozoan Pathogen Cryptosporidium Interdisciplinary Perspectives on Infectious Diseases |
| title | Global Distribution, Public Health and Clinical Impact of the Protozoan Pathogen Cryptosporidium |
| title_full | Global Distribution, Public Health and Clinical Impact of the Protozoan Pathogen Cryptosporidium |
| title_fullStr | Global Distribution, Public Health and Clinical Impact of the Protozoan Pathogen Cryptosporidium |
| title_full_unstemmed | Global Distribution, Public Health and Clinical Impact of the Protozoan Pathogen Cryptosporidium |
| title_short | Global Distribution, Public Health and Clinical Impact of the Protozoan Pathogen Cryptosporidium |
| title_sort | global distribution public health and clinical impact of the protozoan pathogen cryptosporidium |
| url | http://dx.doi.org/10.1155/2010/753512 |
| work_keys_str_mv | AT lorenzaputignani globaldistributionpublichealthandclinicalimpactoftheprotozoanpathogencryptosporidium AT donatomenichella globaldistributionpublichealthandclinicalimpactoftheprotozoanpathogencryptosporidium |