Fc-effector functional antibody assays for SARS-CoV-2 variants of concern

Fc-effector functional antibody assays for SARS-CoV-2 variants of concern

BackgroundThe Fc regions of antibodies mediate important effector cell functions such as antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), antibody-dependent neutrophil phagocytosis (ADNP), and complement-dependent cytotoxicity (CDC). These functions e...

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Bibliographic Details
Main Authors: Xuemin Chen, Grace Li, Caroline Ciric, Theda Gibson, Larry J. Anderson, Christina A. Rostad
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
ADCC
ADNP
ADCP
non-neutralizing antibodies
cytotoxicity
phagocytosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1571835/full
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