Acute severe ulcerative colitis: using JAK-STAT inhibitors for improved clinical outcomes

Acute severe ulcerative colitis: using JAK-STAT inhibitors for improved clinical outcomes

Acute Severe Ulcerative Colitis (ASUC) is a well-known and potentially fatal disease state, characterized by symptoms of systemic toxicity including fever, severe anemia, elevated inflammatory markers, and autonomic instability. The life-threatening nature of this condition requires clinicians to ma...

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Bibliographic Details
Main Authors: Shruthi Karthikeyan, Chetan Ambastha, Kian Keyashian
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Gastroenterology
Subjects:
acute severe ulcerative colitis (ASUC)
infliximab (IFX)
salvage therapies
JAK inhibitors
tofacitinib
upadacitinib
Online Access:https://www.frontiersin.org/articles/10.3389/fgstr.2024.1488288/full
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