EFFICACY EVALUATION OF A MONOCLONAL ANTIBODY AGAINST THE EPIDERMAL GROWTH FACTORS RECEPTOR IN THE MODEL OF SUBCUTANEOUS XENOGRAFT IN IMMUNODEFICIENT MICE

EFFICACY EVALUATION OF A MONOCLONAL ANTIBODY AGAINST THE EPIDERMAL GROWTH FACTORS RECEPTOR IN THE MODEL OF SUBCUTANEOUS XENOGRAFT IN IMMUNODEFICIENT MICE

This article presents the results of the comparative antitumor efficacy study of two test articles of therapeutic humanized monoclonal antibodies against epidermal growth factor receptor (EGFR) manufactured by Russian biopharmaceutical company CJSC “Biocad” and the commercial drug “Erbitux®” (Merck,...

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Bibliographic Details
Main Authors: Ya. Yu. Ustyugov, A. A. Aleksandrov, M. V. Artyukova, M. A. Varavko
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2016-02-01
Series:Сибирский онкологический журнал
Subjects:
a431ns, erbitux®, xenograft, immunodeficient mice, tumor growth inhibition, antitumor efficacy, human epidermoid carcinoma, tumor growth index
Online Access:https://www.siboncoj.ru/jour/article/view/222
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