An integrated model of multiple-condition ChIP-Seq data reveals predeterminants of Cdx2 binding.

Regulatory proteins can bind to different sets of genomic targets in various cell types or conditions. To reliably characterize such condition-specific regulatory binding we introduce MultiGPS, an integrated machine learning approach for the analysis of multiple related ChIP-seq experiments. MultiGP...

Full description

Saved in:
Bibliographic Details
Main Authors: Shaun Mahony, Matthew D Edwards, Esteban O Mazzoni, Richard I Sherwood, Akshay Kakumanu, Carolyn A Morrison, Hynek Wichterle, David K Gifford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003501&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!