PANoptosis in Bacterial Infections: A Double-Edged Sword Balancing Host Immunity and Pathogenesis

PANoptosis in Bacterial Infections: A Double-Edged Sword Balancing Host Immunity and Pathogenesis

PANoptosis is a newly identified programmed cell death pathway that integrates characteristics of apoptosis, pyroptosis, and necroptosis. It plays a dual role in the host immune response to bacterial infections. On one hand, PANoptosis acts as a protective mechanism by inducing the death of infected...

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Bibliographic Details
Main Authors: Xiaoe He, Xiangyan Jiang, Jiayin Guo, Hui Sun, Jing Yang
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pathogens
Subjects:
PANoptosis
programmed cell death
bacterial infection
bacterial infectious disease
host–pathogen interactions
Online Access:https://www.mdpi.com/2076-0817/14/1/43
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