Chemokines
Chemokines are a family of polypeptides that direct the migration of leukocytestoward a site of infection. They play a major role in autoimmune disease and chemokine receptors have recently been found to mediate HIV-1 fusion. In this short review we examine the role of chemokines in host defence and...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2007-01-01
|
| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2007.6 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832552269341523968 |
|---|---|
| author | Richard Horuk |
| author_facet | Richard Horuk |
| author_sort | Richard Horuk |
| collection | DOAJ |
| description | Chemokines are a family of polypeptides that direct the migration of leukocytestoward a site of infection. They play a major role in autoimmune disease and chemokine receptors have recently been found to mediate HIV-1 fusion. In this short review we examine the role of chemokines in host defence and in the pathophysiology of autoimmune diseases. We conclude by discussing various therapeutic approaches that target chemokine receptors and that could be beneficial in disease. |
| format | Article |
| id | doaj-art-025abb1ff4a2415ab68063be2309ae49 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-025abb1ff4a2415ab68063be2309ae492025-02-03T05:58:56ZengWileyThe Scientific World Journal1537-744X2007-01-01722423210.1100/tsw.2007.6ChemokinesRichard Horuk0Department of Immunology, Berlex Biosciences, Richmond, CA, USAChemokines are a family of polypeptides that direct the migration of leukocytestoward a site of infection. They play a major role in autoimmune disease and chemokine receptors have recently been found to mediate HIV-1 fusion. In this short review we examine the role of chemokines in host defence and in the pathophysiology of autoimmune diseases. We conclude by discussing various therapeutic approaches that target chemokine receptors and that could be beneficial in disease.http://dx.doi.org/10.1100/tsw.2007.6 |
| spellingShingle | Richard Horuk Chemokines The Scientific World Journal |
| title | Chemokines |
| title_full | Chemokines |
| title_fullStr | Chemokines |
| title_full_unstemmed | Chemokines |
| title_short | Chemokines |
| title_sort | chemokines |
| url | http://dx.doi.org/10.1100/tsw.2007.6 |
| work_keys_str_mv | AT richardhoruk chemokines |