A novel tertiary lymphoid structure-associated signature accurately predicts patient prognosis and facilitates the selection of personalized treatment strategies for HNSCC

A novel tertiary lymphoid structure-associated signature accurately predicts patient prognosis and facilitates the selection of personalized treatment strategies for HNSCC

BackgroundHead and neck squamous cell carcinoma (HNSCC) is the most common type of head and neck cancer and is characterized by its aggressive nature and variable prognosis and response to immunotherapy. Tertiary lymphoid structures (TLSs) play crucial roles in creating a favourable immune microenvi...

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Bibliographic Details
Main Authors: Jinhao Zhang, Lu Zeng, Guobin Song, Gaoge Peng, Zhezheng Chen, Yamin Yuan, Taowu Chen, Tao Zhong, Shixi Chen, Zhengzhou Luo, Jingang Xiao, Lin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
tertiary lymphatic structure
HNSCC
GSVA
tumour microenvironment
immunotherapy
nomogram
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1551844/full
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