Analysis of synovial fluid Asporin levels in patients with temporomandibular joint disorders
Objective To investigate the changes and clinical significance of synovial fluid Asporin level in patients with temporomandibular joint disorders (TMD). Methods A total of 48 TMD patients who were treated in our hospital from January 2021 to December 2023 due to irritant pain and mouth opening limit...
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Editorial Office of Stomatology
2025-07-01
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| Series: | Kouqiang yixue |
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| Online Access: | https://www.stomatology.cn/fileup/1003-9872/PDF/1753340242649-1430521423.pdf |
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| author | ZHANG Lei, BU Haiwei, XU Tianyu, ZHANG Mingxu, NIU Ping, HUO Feng, LIU Rui |
| author_facet | ZHANG Lei, BU Haiwei, XU Tianyu, ZHANG Mingxu, NIU Ping, HUO Feng, LIU Rui |
| author_sort | ZHANG Lei, BU Haiwei, XU Tianyu, ZHANG Mingxu, NIU Ping, HUO Feng, LIU Rui |
| collection | DOAJ |
| description | Objective To investigate the changes and clinical significance of synovial fluid Asporin level in patients with temporomandibular joint disorders (TMD). Methods A total of 48 TMD patients who were treated in our hospital from January 2021 to December 2023 due to irritant pain and mouth opening limitation were randomly selected as the observation group, and 48 healthy volunteers were selected as the control group. The synovial fluid Asporin levels of the two groups were detected by enzyme-linked immunosorbent assay (ELISA). The difference of synovial fluid Asporin levels between the two groups was compared. The correlation between the synovial fluid Asporin levels and the clinical symptoms of TMD was analyzed. Results The synovial fluid Asporin level in the experimental group was significantly higher than that in the control group (P<0.05). The synovial fluid Asporin level was positively correlated with the pain degree of TMD patients (Rs=0.825, P<0.001), negatively correlated with the degree of mouth opening (Rs=-0.945, P<0.001). Conclusion The level of Asporin in synovial fluid of TMD patients was significantly increased. The level of Asporin in synovial fluid of TMD patients is correlated with the clinical symptoms of TMD, which provides a basis for the diagnosis and evaluation of TMD. |
| format | Article |
| id | doaj-art-0250649adbe94de6af77c56e00ba989b |
| institution | Kabale University |
| issn | 1003-9872 |
| language | zho |
| publishDate | 2025-07-01 |
| publisher | Editorial Office of Stomatology |
| record_format | Article |
| series | Kouqiang yixue |
| spelling | doaj-art-0250649adbe94de6af77c56e00ba989b2025-08-26T06:49:08ZzhoEditorial Office of StomatologyKouqiang yixue1003-98722025-07-0145752552810.13591/j.cnki.kqyx.2025.07.008Analysis of synovial fluid Asporin levels in patients with temporomandibular joint disordersZHANG Lei, BU Haiwei, XU Tianyu, ZHANG Mingxu, NIU Ping, HUO Feng, LIU Rui0Department of Stomatology, The Affiliated Hospital of Chengde Medical College, Chengde 067000, ChinaObjective To investigate the changes and clinical significance of synovial fluid Asporin level in patients with temporomandibular joint disorders (TMD). Methods A total of 48 TMD patients who were treated in our hospital from January 2021 to December 2023 due to irritant pain and mouth opening limitation were randomly selected as the observation group, and 48 healthy volunteers were selected as the control group. The synovial fluid Asporin levels of the two groups were detected by enzyme-linked immunosorbent assay (ELISA). The difference of synovial fluid Asporin levels between the two groups was compared. The correlation between the synovial fluid Asporin levels and the clinical symptoms of TMD was analyzed. Results The synovial fluid Asporin level in the experimental group was significantly higher than that in the control group (P<0.05). The synovial fluid Asporin level was positively correlated with the pain degree of TMD patients (Rs=0.825, P<0.001), negatively correlated with the degree of mouth opening (Rs=-0.945, P<0.001). Conclusion The level of Asporin in synovial fluid of TMD patients was significantly increased. The level of Asporin in synovial fluid of TMD patients is correlated with the clinical symptoms of TMD, which provides a basis for the diagnosis and evaluation of TMD.https://www.stomatology.cn/fileup/1003-9872/PDF/1753340242649-1430521423.pdf|temporomandibular joint disorder|asporin|immunosorbent assay (elisa)|biological marker |
| spellingShingle | ZHANG Lei, BU Haiwei, XU Tianyu, ZHANG Mingxu, NIU Ping, HUO Feng, LIU Rui Analysis of synovial fluid Asporin levels in patients with temporomandibular joint disorders Kouqiang yixue |temporomandibular joint disorder|asporin|immunosorbent assay (elisa)|biological marker |
| title | Analysis of synovial fluid Asporin levels in patients with temporomandibular joint disorders |
| title_full | Analysis of synovial fluid Asporin levels in patients with temporomandibular joint disorders |
| title_fullStr | Analysis of synovial fluid Asporin levels in patients with temporomandibular joint disorders |
| title_full_unstemmed | Analysis of synovial fluid Asporin levels in patients with temporomandibular joint disorders |
| title_short | Analysis of synovial fluid Asporin levels in patients with temporomandibular joint disorders |
| title_sort | analysis of synovial fluid asporin levels in patients with temporomandibular joint disorders |
| topic | |temporomandibular joint disorder|asporin|immunosorbent assay (elisa)|biological marker |
| url | https://www.stomatology.cn/fileup/1003-9872/PDF/1753340242649-1430521423.pdf |
| work_keys_str_mv | AT zhangleibuhaiweixutianyuzhangmingxuniupinghuofengliurui analysisofsynovialfluidasporinlevelsinpatientswithtemporomandibularjointdisorders |