The effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery: a randomized controlled study

Abstract Background After open heart surgery, patients experience high levels of pain at the sternotomy incision site and around the chest tube(s), affecting their recovery. This study was conducted to determine the effects of local anesthetic application around the sternotomy incision site and ches...

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Main Authors: Hatice AZİZOĞLU, Mehmet AŞAM, Zeynep GÜRKAN, Yasemin BOZKURT, Canan DEMİR
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-025-04493-2
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author Hatice AZİZOĞLU
Mehmet AŞAM
Zeynep GÜRKAN
Yasemin BOZKURT
Canan DEMİR
author_facet Hatice AZİZOĞLU
Mehmet AŞAM
Zeynep GÜRKAN
Yasemin BOZKURT
Canan DEMİR
author_sort Hatice AZİZOĞLU
collection DOAJ
description Abstract Background After open heart surgery, patients experience high levels of pain at the sternotomy incision site and around the chest tube(s), affecting their recovery. This study was conducted to determine the effects of local anesthetic application around the sternotomy incision site and chest tube(s) on the amount of opioids used and recovery after surgery in patients undergoing open heart surgery. Methods This randomized controlled experimental study was conducted with a total of 60 patients, with 30 patients in the experimental group and 30 patients in the control group. In the experimental group, LIDOFAST 40 mg/2 ml + 0.025 mg/2 ml, a local anesthetic agent, was applied to the postoperative sternotomy incision site and around the chest tube(s) in addition to routine treatment. Patients in the control group received only routine treatment. Data were collected using the “Descriptive Characteristics Form” and the “Postoperative Recovery Index”. Results It was observed that postoperative pain started later, opioid consumption decreased, and postoperative recovery was faster in the experimental group. As the number of chest tubes increased, recovery was delayed in all groups, and as the number of opioids used increased, postoperative recovery was negatively affected in the control group. Conclusions In this study, local anesthetic application to the sternotomy incision site and around the chest tubes after open heart surgery was found to reduce postoperative opioid consumption and positively affect recovery. Trial registration Current Controlled Trials NCT06642077 (Retrospectively registered).
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spelling doaj-art-0249aafc12184e8a9ccfa04bfef790122025-02-02T12:07:49ZengBMCBMC Cardiovascular Disorders1471-22612025-02-0125111110.1186/s12872-025-04493-2The effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery: a randomized controlled studyHatice AZİZOĞLU0Mehmet AŞAM1Zeynep GÜRKAN2Yasemin BOZKURT3Canan DEMİR4Faculty of Health Sciences, Nursing, Van Yüzüncü Yıl UniversityVan Training and Research HospitalInstitute of Health Sciences, Atatürk UniversityVan Training and Research HospitalHealth Services Vocational High School, Van Yüzüncü Yıl UniversityAbstract Background After open heart surgery, patients experience high levels of pain at the sternotomy incision site and around the chest tube(s), affecting their recovery. This study was conducted to determine the effects of local anesthetic application around the sternotomy incision site and chest tube(s) on the amount of opioids used and recovery after surgery in patients undergoing open heart surgery. Methods This randomized controlled experimental study was conducted with a total of 60 patients, with 30 patients in the experimental group and 30 patients in the control group. In the experimental group, LIDOFAST 40 mg/2 ml + 0.025 mg/2 ml, a local anesthetic agent, was applied to the postoperative sternotomy incision site and around the chest tube(s) in addition to routine treatment. Patients in the control group received only routine treatment. Data were collected using the “Descriptive Characteristics Form” and the “Postoperative Recovery Index”. Results It was observed that postoperative pain started later, opioid consumption decreased, and postoperative recovery was faster in the experimental group. As the number of chest tubes increased, recovery was delayed in all groups, and as the number of opioids used increased, postoperative recovery was negatively affected in the control group. Conclusions In this study, local anesthetic application to the sternotomy incision site and around the chest tubes after open heart surgery was found to reduce postoperative opioid consumption and positively affect recovery. Trial registration Current Controlled Trials NCT06642077 (Retrospectively registered).https://doi.org/10.1186/s12872-025-04493-2Cardiovascular surgeryPain managementLocal anestheticsRecovery after surgeryOpioids
spellingShingle Hatice AZİZOĞLU
Mehmet AŞAM
Zeynep GÜRKAN
Yasemin BOZKURT
Canan DEMİR
The effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery: a randomized controlled study
BMC Cardiovascular Disorders
Cardiovascular surgery
Pain management
Local anesthetics
Recovery after surgery
Opioids
title The effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery: a randomized controlled study
title_full The effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery: a randomized controlled study
title_fullStr The effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery: a randomized controlled study
title_full_unstemmed The effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery: a randomized controlled study
title_short The effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery: a randomized controlled study
title_sort effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery a randomized controlled study
topic Cardiovascular surgery
Pain management
Local anesthetics
Recovery after surgery
Opioids
url https://doi.org/10.1186/s12872-025-04493-2
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