Strenuous Exercise-Induced Tremendously Elevated Transaminases Levels in a Healthy Adult: A Diagnostic Dilemma
The liver function test (LFT) is a commonly performed test in clinical practice in order to assess well-being of the liver; however, derangement in liver enzymes, however, may not necessarily imply an underlying liver pathology. The standard liver function test measures alanine aminotransferase (ALT...
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Language: | English |
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Wiley
2021-01-01
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Series: | Case Reports in Hepatology |
Online Access: | http://dx.doi.org/10.1155/2021/6653266 |
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author | Prabin Khatri Aryan Neupane Suman Raj Sapkota Bibhav Bashyal Dipesh Sharma Ashmita Chhetri K. C. Chirag Ashish Banjade Priyanka Sapkota Subarna. Bhandari |
author_facet | Prabin Khatri Aryan Neupane Suman Raj Sapkota Bibhav Bashyal Dipesh Sharma Ashmita Chhetri K. C. Chirag Ashish Banjade Priyanka Sapkota Subarna. Bhandari |
author_sort | Prabin Khatri |
collection | DOAJ |
description | The liver function test (LFT) is a commonly performed test in clinical practice in order to assess well-being of the liver; however, derangement in liver enzymes, however, may not necessarily imply an underlying liver pathology. The standard liver function test measures alanine aminotransferase (ALT), aspartate aminotransferase (AST), alanine phosphatase (ALP), bilirubin levels (total, direct, and indirect), proteins (total protein and albumin), and PT-INR (prothrombin time and international normalized ratio). In addition to common causes, liver enzyme levels can also be elevated due to extrahepatic causes, such as muscular injury can elevate transaminases levels. Here in, we present a case of an asymptomatic healthy male who was doing vigorous exercise and presented with reports of elevated transaminase levels. During evaluation of the case, most of his reports came to be within normal range. Additionally, when reevaluated after discontinuation of vigorous exercise, 3 weeks later and then a month later, his liver enzyme levels were observed to be within normal range. Hence, we suspect that muscle damage-induced transaminitis might not have been considered in the differential diagnosis during the evaluation of a patient with raised transaminases levels and also suggest that it should be kept as a differential in the given scenario. |
format | Article |
id | doaj-art-022ee112f18f4392b658914cc4a2a086 |
institution | Kabale University |
issn | 2090-6587 2090-6595 |
language | English |
publishDate | 2021-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Hepatology |
spelling | doaj-art-022ee112f18f4392b658914cc4a2a0862025-02-03T06:43:34ZengWileyCase Reports in Hepatology2090-65872090-65952021-01-01202110.1155/2021/66532666653266Strenuous Exercise-Induced Tremendously Elevated Transaminases Levels in a Healthy Adult: A Diagnostic DilemmaPrabin Khatri0Aryan Neupane1Suman Raj Sapkota2Bibhav Bashyal3Dipesh Sharma4Ashmita Chhetri5K. C. Chirag6Ashish Banjade7Priyanka Sapkota8Subarna. Bhandari9Universal College of Medical Sciences & Teaching Hospital, Bhairahawa, NepalUniversal College of Medical Sciences & Teaching Hospital, Bhairahawa, NepalUniversal College of Medical Sciences & Teaching Hospital, Bhairahawa, NepalUniversal College of Medical Sciences & Teaching Hospital, Bhairahawa, NepalUniversal College of Medical Sciences & Teaching Hospital, Bhairahawa, NepalUniversal College of Medical Sciences & Teaching Hospital, Bhairahawa, NepalUniversal College of Medical Sciences & Teaching Hospital, Bhairahawa, NepalUniversal College of Medical Sciences & Teaching Hospital, Bhairahawa, NepalUniversal College of Medical Sciences & Teaching Hospital, Bhairahawa, NepalUniversal College of Medical Sciences & Teaching Hospital, Bhairahawa, NepalThe liver function test (LFT) is a commonly performed test in clinical practice in order to assess well-being of the liver; however, derangement in liver enzymes, however, may not necessarily imply an underlying liver pathology. The standard liver function test measures alanine aminotransferase (ALT), aspartate aminotransferase (AST), alanine phosphatase (ALP), bilirubin levels (total, direct, and indirect), proteins (total protein and albumin), and PT-INR (prothrombin time and international normalized ratio). In addition to common causes, liver enzyme levels can also be elevated due to extrahepatic causes, such as muscular injury can elevate transaminases levels. Here in, we present a case of an asymptomatic healthy male who was doing vigorous exercise and presented with reports of elevated transaminase levels. During evaluation of the case, most of his reports came to be within normal range. Additionally, when reevaluated after discontinuation of vigorous exercise, 3 weeks later and then a month later, his liver enzyme levels were observed to be within normal range. Hence, we suspect that muscle damage-induced transaminitis might not have been considered in the differential diagnosis during the evaluation of a patient with raised transaminases levels and also suggest that it should be kept as a differential in the given scenario.http://dx.doi.org/10.1155/2021/6653266 |
spellingShingle | Prabin Khatri Aryan Neupane Suman Raj Sapkota Bibhav Bashyal Dipesh Sharma Ashmita Chhetri K. C. Chirag Ashish Banjade Priyanka Sapkota Subarna. Bhandari Strenuous Exercise-Induced Tremendously Elevated Transaminases Levels in a Healthy Adult: A Diagnostic Dilemma Case Reports in Hepatology |
title | Strenuous Exercise-Induced Tremendously Elevated Transaminases Levels in a Healthy Adult: A Diagnostic Dilemma |
title_full | Strenuous Exercise-Induced Tremendously Elevated Transaminases Levels in a Healthy Adult: A Diagnostic Dilemma |
title_fullStr | Strenuous Exercise-Induced Tremendously Elevated Transaminases Levels in a Healthy Adult: A Diagnostic Dilemma |
title_full_unstemmed | Strenuous Exercise-Induced Tremendously Elevated Transaminases Levels in a Healthy Adult: A Diagnostic Dilemma |
title_short | Strenuous Exercise-Induced Tremendously Elevated Transaminases Levels in a Healthy Adult: A Diagnostic Dilemma |
title_sort | strenuous exercise induced tremendously elevated transaminases levels in a healthy adult a diagnostic dilemma |
url | http://dx.doi.org/10.1155/2021/6653266 |
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