Impact of acute stress exposure on genome-wide DNA methylation

Impact of acute stress exposure on genome-wide DNA methylation

Abstract DNA methylation (DNAm) is a stable epigenetic modification, yet plasticity in DNAm is associated with exposure to a broad range of experiences. Evidence from animal studies suggests that acute stress can induce DNAm changes in adulthood. However, there has been limited exploration of plasti...

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Bibliographic Details
Main Authors: Melissa Miller, Ciara McAfee, Robin D. Brown, Shelby Sears, Cole Krautkramer, Rhea Gogia, Dennis Wylie, Robert A. Josephs, Frances A. Champagne
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Acute stress
DNA methylation
Cortisol
Psychological stress
Epigenetic age
Online Access:https://doi.org/10.1038/s41598-025-09299-y
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