The use of human tissue surrogates in anatomical modeling for gunshot wounds simulations: an overview about “how to do” experimental terminal ballistics

Human tissue simulating materials are currently used in scientific research mainly because they help to avoid possible ethical issues, unlike what happens with studies involving live animals and/or human cadavers. The use of ballistic gelatin as a human soft tissue surrogate stands out, although oth...

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Main Authors: Lucas Meciano Pereira dos Santos, Marcelo Rodrigues da Cunha, Carlos Henrique Bertoni Reis, Daniela Vieira Buchaim, Ana Paula Bernardes da Rosa, Leandro Moreira Tempest, José Augusto Parola da Cruz, Rogério Leone Buchaim, João Paulo Mardegan Issa
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Bioengineering and Biotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1536423/full
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author Lucas Meciano Pereira dos Santos
Marcelo Rodrigues da Cunha
Carlos Henrique Bertoni Reis
Daniela Vieira Buchaim
Daniela Vieira Buchaim
Ana Paula Bernardes da Rosa
Leandro Moreira Tempest
José Augusto Parola da Cruz
Rogério Leone Buchaim
Rogério Leone Buchaim
João Paulo Mardegan Issa
João Paulo Mardegan Issa
author_facet Lucas Meciano Pereira dos Santos
Marcelo Rodrigues da Cunha
Carlos Henrique Bertoni Reis
Daniela Vieira Buchaim
Daniela Vieira Buchaim
Ana Paula Bernardes da Rosa
Leandro Moreira Tempest
José Augusto Parola da Cruz
Rogério Leone Buchaim
Rogério Leone Buchaim
João Paulo Mardegan Issa
João Paulo Mardegan Issa
author_sort Lucas Meciano Pereira dos Santos
collection DOAJ
description Human tissue simulating materials are currently used in scientific research mainly because they help to avoid possible ethical issues, unlike what happens with studies involving live animals and/or human cadavers. The use of ballistic gelatin as a human soft tissue surrogate stands out, although other types of materials can be used, including polyurethane and polydimethylsiloxane in the simulation of bones and skin respectively, not to mention some computational models that completely replace the physical use of surrogate models for gunshot wound simulation. The use of human tissue surrogates can be useful in reconstructing the dynamics of a crime scene when important forensic traces cannot be found. In the absence of projectiles but in possession of the possible firearm used in the crime, for example, it is possible to verify whether the weapon in question actually fired the fatal gunshot by comparing the injury found on the victim with the injury produced on the simulant material that best represents the anatomical area impacted, as indicated in the literature. Thus, scientific advances in experimental research in terminal ballistics with tissue surrogates can positively impact applied forensic sciences in the search for better technical assistance to the justice system in solving criminal situations.
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publisher Frontiers Media S.A.
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spelling doaj-art-020738a882e24108b13988e3fe6a92c42025-01-24T07:13:53ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-01-011310.3389/fbioe.2025.15364231536423The use of human tissue surrogates in anatomical modeling for gunshot wounds simulations: an overview about “how to do” experimental terminal ballisticsLucas Meciano Pereira dos Santos0Marcelo Rodrigues da Cunha1Carlos Henrique Bertoni Reis2Daniela Vieira Buchaim3Daniela Vieira Buchaim4Ana Paula Bernardes da Rosa5Leandro Moreira Tempest6José Augusto Parola da Cruz7Rogério Leone Buchaim8Rogério Leone Buchaim9João Paulo Mardegan Issa10João Paulo Mardegan Issa11Department of Pathology and Legal Medicine, School of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, BrazilPostgraduate Program in Health Sciences, Faculty of Medicine of Jundiaí (FMJ), Jundiaí, BrazilPostgraduate Program in Structural and Functional Interactions in Rehabilitation, Postgraduate Department, University of Marilia (UNIMAR), Marilia, BrazilFaculty of Medicine of Bauru, University of São Paulo (FMBRU-USP), Bauru, BrazilMedical School, University Center of Adamantina (FAI), Adamantina, BrazilUniversity Center of the North of São Paulo (UNORTE), São José Do Rio Preto, BrazilUniversity Center of the North of São Paulo (UNORTE), São José Do Rio Preto, BrazilUniversity Center of the North of São Paulo (UNORTE), São José Do Rio Preto, BrazilFaculty of Medicine of Bauru, University of São Paulo (FMBRU-USP), Bauru, BrazilDepartment of Biological Sciences, School of Dentistry of Bauru, University of São Paulo (FOB-USP), Bauru, BrazilDepartment of Pathology and Legal Medicine, School of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto, BrazilDepartment of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo (FORP-USP), Ribeirão Preto, BrazilHuman tissue simulating materials are currently used in scientific research mainly because they help to avoid possible ethical issues, unlike what happens with studies involving live animals and/or human cadavers. The use of ballistic gelatin as a human soft tissue surrogate stands out, although other types of materials can be used, including polyurethane and polydimethylsiloxane in the simulation of bones and skin respectively, not to mention some computational models that completely replace the physical use of surrogate models for gunshot wound simulation. The use of human tissue surrogates can be useful in reconstructing the dynamics of a crime scene when important forensic traces cannot be found. In the absence of projectiles but in possession of the possible firearm used in the crime, for example, it is possible to verify whether the weapon in question actually fired the fatal gunshot by comparing the injury found on the victim with the injury produced on the simulant material that best represents the anatomical area impacted, as indicated in the literature. Thus, scientific advances in experimental research in terminal ballistics with tissue surrogates can positively impact applied forensic sciences in the search for better technical assistance to the justice system in solving criminal situations.https://www.frontiersin.org/articles/10.3389/fbioe.2025.1536423/fullforensic pathologyballisticsgunshot woundsanatomic modelspolymersgelatin
spellingShingle Lucas Meciano Pereira dos Santos
Marcelo Rodrigues da Cunha
Carlos Henrique Bertoni Reis
Daniela Vieira Buchaim
Daniela Vieira Buchaim
Ana Paula Bernardes da Rosa
Leandro Moreira Tempest
José Augusto Parola da Cruz
Rogério Leone Buchaim
Rogério Leone Buchaim
João Paulo Mardegan Issa
João Paulo Mardegan Issa
The use of human tissue surrogates in anatomical modeling for gunshot wounds simulations: an overview about “how to do” experimental terminal ballistics
Frontiers in Bioengineering and Biotechnology
forensic pathology
ballistics
gunshot wounds
anatomic models
polymers
gelatin
title The use of human tissue surrogates in anatomical modeling for gunshot wounds simulations: an overview about “how to do” experimental terminal ballistics
title_full The use of human tissue surrogates in anatomical modeling for gunshot wounds simulations: an overview about “how to do” experimental terminal ballistics
title_fullStr The use of human tissue surrogates in anatomical modeling for gunshot wounds simulations: an overview about “how to do” experimental terminal ballistics
title_full_unstemmed The use of human tissue surrogates in anatomical modeling for gunshot wounds simulations: an overview about “how to do” experimental terminal ballistics
title_short The use of human tissue surrogates in anatomical modeling for gunshot wounds simulations: an overview about “how to do” experimental terminal ballistics
title_sort use of human tissue surrogates in anatomical modeling for gunshot wounds simulations an overview about how to do experimental terminal ballistics
topic forensic pathology
ballistics
gunshot wounds
anatomic models
polymers
gelatin
url https://www.frontiersin.org/articles/10.3389/fbioe.2025.1536423/full
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