Anti-tumor potential of Harmine and its derivatives: recent trends and advancements

Anti-tumor potential of Harmine and its derivatives: recent trends and advancements

Abstract Harmine is a β-carboline alkaloid derived from Peganum harmala, showing a solid antitumor potential in different types of human cancer cells. Unfortunately, the clinical application of this natural alkaloid has been impeded till now by severe toxic side effects, especially neurotoxicity, be...

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Main Authors: Hemant Joshi, Sakshi Bhushan, Tanisha Dimri, Deepak Sharma, Katrin Sak, Abhishek Chauhan, Ritu Chauhan, Shafiul Haque, Faraz Ahmad, Manoj Kumar, Hardeep Singh Tuli, Damandeep Kaur
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Discover Oncology
Subjects:
Harmine
Alkaloid
Anti-cancer
Natural product
Cancer therapeutics
Online Access:https://doi.org/10.1007/s12672-025-01893-w
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