Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis

A 38-year-old hypertensive male with a smoking history presented to the emergency room with significant hemoptysis, arthritis, and a purpuric rash. Other findings included a dropping hemoglobin and acute kidney injury with microscopic hematuria. The pulmonary computed tomography was significant for...

Full description

Saved in:
Bibliographic Details
Main Authors: Ahmed Alhazmi, Mohamed Moulaye Cheikh, Rola Yousef Hassan
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2020/3079869
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832566176726646784
author Ahmed Alhazmi
Mohamed Moulaye Cheikh
Rola Yousef Hassan
author_facet Ahmed Alhazmi
Mohamed Moulaye Cheikh
Rola Yousef Hassan
author_sort Ahmed Alhazmi
collection DOAJ
description A 38-year-old hypertensive male with a smoking history presented to the emergency room with significant hemoptysis, arthritis, and a purpuric rash. Other findings included a dropping hemoglobin and acute kidney injury with microscopic hematuria. The pulmonary computed tomography was significant for alveolar hemorrhage and a rarely reported pneumomediastinum. Along with this constellation of findings, a positive antiproteinase 3 helped to confirm this patient’s diagnosis of granulomatosis with polyangiitis. Treatment commenced with sessions of plasma exchange and pulse steroids along with cyclophosphamide infusions. The patient had since improved and made a full recovery. This case report highlights the rarely described pneumomediastinum in association with vasculitides.
format Article
id doaj-art-01da2a3d31f64f77a9bd012c7c19611b
institution Kabale University
issn 2090-6889
2090-6897
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Case Reports in Rheumatology
spelling doaj-art-01da2a3d31f64f77a9bd012c7c19611b2025-02-03T01:04:47ZengWileyCase Reports in Rheumatology2090-68892090-68972020-01-01202010.1155/2020/30798693079869Pneumomediastinum as a Manifestation of Granulomatosis with PolyangiitisAhmed Alhazmi0Mohamed Moulaye Cheikh1Rola Yousef Hassan2Department of Medicine, Division of Rheumatology, King Fahad Armed Forces Hospital, Jeddah, Saudi ArabiaDoctor Soliman Fakeeh Hospital, Jeddah, Saudi ArabiaDepartment of Medicine, Division of Rheumatology, King Fahad Armed Forces Hospital, Jeddah, Saudi ArabiaA 38-year-old hypertensive male with a smoking history presented to the emergency room with significant hemoptysis, arthritis, and a purpuric rash. Other findings included a dropping hemoglobin and acute kidney injury with microscopic hematuria. The pulmonary computed tomography was significant for alveolar hemorrhage and a rarely reported pneumomediastinum. Along with this constellation of findings, a positive antiproteinase 3 helped to confirm this patient’s diagnosis of granulomatosis with polyangiitis. Treatment commenced with sessions of plasma exchange and pulse steroids along with cyclophosphamide infusions. The patient had since improved and made a full recovery. This case report highlights the rarely described pneumomediastinum in association with vasculitides.http://dx.doi.org/10.1155/2020/3079869
spellingShingle Ahmed Alhazmi
Mohamed Moulaye Cheikh
Rola Yousef Hassan
Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis
Case Reports in Rheumatology
title Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis
title_full Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis
title_fullStr Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis
title_full_unstemmed Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis
title_short Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis
title_sort pneumomediastinum as a manifestation of granulomatosis with polyangiitis
url http://dx.doi.org/10.1155/2020/3079869
work_keys_str_mv AT ahmedalhazmi pneumomediastinumasamanifestationofgranulomatosiswithpolyangiitis
AT mohamedmoulayecheikh pneumomediastinumasamanifestationofgranulomatosiswithpolyangiitis
AT rolayousefhassan pneumomediastinumasamanifestationofgranulomatosiswithpolyangiitis