Integrating machine learning with mendelian randomization for unveiling causal gene networks in glioblastoma multiforme
Abstract Background Glioblastoma multiforme (GBM) is a highly aggressive brain cancer with poor prognosis and limited treatment options. Despite advances in understanding its molecular mechanisms, effective therapeutic strategies remain elusive due to the tumor’s genetic complexity and heterogeneity...
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Main Authors: | Lixin Du, Pan Wang, Xiaoting Qiu, Zhigang Li, Jianlan Ma, Pengfei Chen |
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Format: | Article |
Language: | English |
Published: |
Springer
2025-01-01
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Series: | Discover Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1007/s12672-025-01792-0 |
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