Rapid Synthesis of Bradykinin in Solution
Two variants of the two-phase-purification method are examined, using the preparation of bradykinin as a model. In one synthesis, intermediate purification by liquid-liquid extraction was carried out after each completed elongation, in the other, new variant, the extractions were performed after th...
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
1981-10-01
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| Series: | CHIMIA |
| Online Access: | https://www.chimia.ch/chimia/article/view/9537 |
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| _version_ | 1850140256943210496 |
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| author | Hanspeter Rolli Conrad H. Schneider |
| author_facet | Hanspeter Rolli Conrad H. Schneider |
| author_sort | Hanspeter Rolli |
| collection | DOAJ |
| description |
Two variants of the two-phase-purification method are examined, using the preparation of bradykinin as a model. In one synthesis, intermediate purification by liquid-liquid extraction was carried out after each completed elongation, in the other, new variant, the extractions were performed after the deprotection steps. If not hampered by technical difficulties the second variant is more efficient.
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| format | Article |
| id | doaj-art-01a622abdf734e19b5e2c90d81b25f2c |
| institution | OA Journals |
| issn | 0009-4293 2673-2424 |
| language | deu |
| publishDate | 1981-10-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj-art-01a622abdf734e19b5e2c90d81b25f2c2025-08-20T02:29:54ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24241981-10-01351010.2533/chimia.1981.403Rapid Synthesis of Bradykinin in SolutionHanspeter Rolli0Conrad H. Schneider1Institute for Clinical Immunology, Inselspital, 3010 Bern; Institute for Organic Chemistry, Freiestrasse 3, 3012 BernInstitute for Clinical Immunology, Inselspital, 3010 Bern; Institute for Organic Chemistry, Freiestrasse 3, 3012 Bern Two variants of the two-phase-purification method are examined, using the preparation of bradykinin as a model. In one synthesis, intermediate purification by liquid-liquid extraction was carried out after each completed elongation, in the other, new variant, the extractions were performed after the deprotection steps. If not hampered by technical difficulties the second variant is more efficient. https://www.chimia.ch/chimia/article/view/9537 |
| spellingShingle | Hanspeter Rolli Conrad H. Schneider Rapid Synthesis of Bradykinin in Solution CHIMIA |
| title | Rapid Synthesis of Bradykinin in Solution |
| title_full | Rapid Synthesis of Bradykinin in Solution |
| title_fullStr | Rapid Synthesis of Bradykinin in Solution |
| title_full_unstemmed | Rapid Synthesis of Bradykinin in Solution |
| title_short | Rapid Synthesis of Bradykinin in Solution |
| title_sort | rapid synthesis of bradykinin in solution |
| url | https://www.chimia.ch/chimia/article/view/9537 |
| work_keys_str_mv | AT hanspeterrolli rapidsynthesisofbradykinininsolution AT conradhschneider rapidsynthesisofbradykinininsolution |