Understanding the impact of lifestyle and demographic factors on DNA fragmentation index (DFI) among infertile men

Understanding the impact of lifestyle and demographic factors on DNA fragmentation index (DFI) among infertile men

Abstract Background Sperm DNA fragmentation detection methods include SCSA, SCD, COMET assay, and TUNEL. In 2021, the DFI test became the first evidence-based sperm DNA integrity test included in international guidelines. However, limited data exists from Nigeria. This study explores the relationshi...

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Main Authors: Abayomi Bolaji Ajayi, Victor Ajayi, Kazeem Adewale Osuolale, Ngozi Obi, Roselyn Obasa-Gbadebo, Toluwanimi Balogun, Anuoluwa Alaka, Olaoluwa Musa, Edith Omokhegbele
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Urology
Subjects:
Sperm DNA fragmentation index (DFI)
Male infertility
Semen analysis
DNA integrity
Sperm quality
Online Access:https://doi.org/10.1186/s12894-025-01883-8
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https://doi.org/10.1186/s12894-025-01883-8

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