Proteomic analysis of the Treponema pallidum subsp. pallidum SS14 strain: coverage and comparison with the Nichols strain proteome

Proteomic analysis of the Treponema pallidum subsp. pallidum SS14 strain: coverage and comparison with the Nichols strain proteome

IntroductionStrains of the syphilis spirochete, Treponema pallidum ssp. pallidum, group into one of two deep-branching clades: the Nichols clade or the globally dominant Street Strain 14 (SS14) clade. To date, in-depth proteome-wide analyses have focused on Nichols clade strains.MethodsThe T. pallid...

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Bibliographic Details
Main Authors: Simon Houston, Steven Marshall, Alloysius Gomez, Caroline E. Cameron
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Microbiology
Subjects:
Treponema pallidum
syphilis
proteomics
outer membrane proteins
vaccine candidates
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1505893/full
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