Clustering cell nuclei on microgrooves for disease diagnosis using deep learning
Abstract Various diseases including laminopathies and certain types of cancer are associated with abnormal nuclear mechanical properties that influence cellular and nuclear deformations in complex environments. Recently, microgroove substrates designed to mimic the anisotropic topography of the base...
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| Main Authors: | Bettina Roellinger, Francois Thenier, Claire Leclech, Catherine Coirault, Elsa Angelini, Abdul I. Barakat |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-05788-2 |
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