The Antibacterial Activity of Bajakah Tampala Extracts (Spatholobus littoralis Hassk.) Mouthwash Formulation Inhibited Dental Plaque against Streptococcus mutans
Dental plaque is the main cause of dental caries caused by Streptococcus mutans, with a high prevalence in Indonesia. Currently, the mouthwash market contains high levels of alcohol, which can cause long-term side effects. Tampala bajakah root (Spatholobus littoralis) is used in traditional medicine...
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| Format: | Article |
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LPPT Universitas Gadjah Mada
2024-08-01
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| Series: | Journal of Food and Pharmaceutical Sciences |
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| Online Access: | https://jurnal.ugm.ac.id/v3/JFPS/article/view/15147/4837 |
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| author | Rikhaturhohmah Rospadila Dwi Adrila Widiya Dwi Handayani Rasyani Ananda Alifvia Suprapto Nofran Putra Pratama Mitsalina Fildzah Arifah |
| author_facet | Rikhaturhohmah Rospadila Dwi Adrila Widiya Dwi Handayani Rasyani Ananda Alifvia Suprapto Nofran Putra Pratama Mitsalina Fildzah Arifah |
| author_sort | Rikhaturhohmah |
| collection | DOAJ |
| description | Dental plaque is the main cause of dental caries caused by Streptococcus mutans, with a high prevalence in Indonesia. Currently, the mouthwash market contains high levels of alcohol, which can cause long-term side effects. Tampala bajakah root (Spatholobus littoralis) is used in traditional medicine for the Dayak community in Central Kalimantan. Bajakah Tampala root has antibacterial activity produced by flavonoids and phenolic compounds. The development of herbal cosmetics can be achieved by Bajakah Tampala mouthwash formulations to prevent dental plaque caused by Streptococcus mutans infection. In this study, ultrasound-assisted extraction (UBT) and infusion (IBT) derived the active compounds of Bajakah Tampala root extract. The various concentrations of UBT (20–80%) and IBT (10%) were evaluated for antibacterial activity using the disk diffusion method. The results showed that positive control and 80% UBT have antibacterial activity higher than other extracts, with an inhibition zone of 14,01±2,70 mm. Based on these results, an effective mouthwash dosage formulation can be developed at 80% UBT. The formulation evaluation of mouthwash assessed viscosity, homogeneity, pH, and organoleptic test. The UBT mouthwash product has qualified formulation evaluation parameters. This research contributed to the innovation of herbal cosmetics by developing the potential of Indonesian medicinal plants |
| format | Article |
| id | doaj-art-01612b949a694c36a649f3aae1fdfc33 |
| institution | Kabale University |
| issn | 2089-7200 2339-0948 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | LPPT Universitas Gadjah Mada |
| record_format | Article |
| series | Journal of Food and Pharmaceutical Sciences |
| spelling | doaj-art-01612b949a694c36a649f3aae1fdfc332025-01-24T09:53:37ZengLPPT Universitas Gadjah MadaJournal of Food and Pharmaceutical Sciences2089-72002339-09482024-08-0112215816810.22146/jfps.15147The Antibacterial Activity of Bajakah Tampala Extracts (Spatholobus littoralis Hassk.) Mouthwash Formulation Inhibited Dental Plaque against Streptococcus mutansRikhaturhohmah0Rospadila Dwi Adrila1Widiya Dwi Handayani2Rasyani3Ananda Alifvia Suprapto4Nofran Putra Pratama5Mitsalina Fildzah Arifah6Universitas Jenderal Achmad Yani, Jl. Ringroad Barat, Gamping Kidul, Ambarketawang, Kec. Gamping, Kabupaten SlemanYogyakarta, IndonesiaUniversitas Jenderal Achmad Yani, Jl. Ringroad Barat, Gamping Kidul, Ambarketawang, Kec. Gamping, Kabupaten SlemanYogyakarta, IndonesiaUniversitas Jenderal Achmad Yani, Jl. Ringroad Barat, Gamping Kidul, Ambarketawang, Kec. Gamping, Kabupaten SlemanYogyakarta, IndonesiaUniversitas Jenderal Achmad Yani, Jl. Ringroad Barat, Gamping Kidul, Ambarketawang, Kec. Gamping, Kabupaten SlemanYogyakarta, IndonesiaUniversitas Jenderal Achmad Yani, Jl. Ringroad Barat, Gamping Kidul, Ambarketawang, Kec. Gamping, Kabupaten SlemanYogyakarta, IndonesiaUniversitas Jenderal Achmad Yani, Jl. Ringroad Barat, Gamping Kidul, Ambarketawang, Kec. Gamping, Kabupaten SlemanYogyakarta, IndonesiaUniversitas Jenderal Achmad Yani, Jl. Ringroad Barat, Gamping Kidul, Ambarketawang, Kec. Gamping, Kabupaten SlemanYogyakarta, IndonesiaDental plaque is the main cause of dental caries caused by Streptococcus mutans, with a high prevalence in Indonesia. Currently, the mouthwash market contains high levels of alcohol, which can cause long-term side effects. Tampala bajakah root (Spatholobus littoralis) is used in traditional medicine for the Dayak community in Central Kalimantan. Bajakah Tampala root has antibacterial activity produced by flavonoids and phenolic compounds. The development of herbal cosmetics can be achieved by Bajakah Tampala mouthwash formulations to prevent dental plaque caused by Streptococcus mutans infection. In this study, ultrasound-assisted extraction (UBT) and infusion (IBT) derived the active compounds of Bajakah Tampala root extract. The various concentrations of UBT (20–80%) and IBT (10%) were evaluated for antibacterial activity using the disk diffusion method. The results showed that positive control and 80% UBT have antibacterial activity higher than other extracts, with an inhibition zone of 14,01±2,70 mm. Based on these results, an effective mouthwash dosage formulation can be developed at 80% UBT. The formulation evaluation of mouthwash assessed viscosity, homogeneity, pH, and organoleptic test. The UBT mouthwash product has qualified formulation evaluation parameters. This research contributed to the innovation of herbal cosmetics by developing the potential of Indonesian medicinal plantshttps://jurnal.ugm.ac.id/v3/JFPS/article/view/15147/4837bajakah tampalaantibacterial activitymouthwashherbal cosmeticstreptococcus mutans |
| spellingShingle | Rikhaturhohmah Rospadila Dwi Adrila Widiya Dwi Handayani Rasyani Ananda Alifvia Suprapto Nofran Putra Pratama Mitsalina Fildzah Arifah The Antibacterial Activity of Bajakah Tampala Extracts (Spatholobus littoralis Hassk.) Mouthwash Formulation Inhibited Dental Plaque against Streptococcus mutans Journal of Food and Pharmaceutical Sciences bajakah tampala antibacterial activity mouthwash herbal cosmetic streptococcus mutans |
| title | The Antibacterial Activity of Bajakah Tampala Extracts (Spatholobus littoralis Hassk.) Mouthwash Formulation Inhibited Dental Plaque against Streptococcus mutans |
| title_full | The Antibacterial Activity of Bajakah Tampala Extracts (Spatholobus littoralis Hassk.) Mouthwash Formulation Inhibited Dental Plaque against Streptococcus mutans |
| title_fullStr | The Antibacterial Activity of Bajakah Tampala Extracts (Spatholobus littoralis Hassk.) Mouthwash Formulation Inhibited Dental Plaque against Streptococcus mutans |
| title_full_unstemmed | The Antibacterial Activity of Bajakah Tampala Extracts (Spatholobus littoralis Hassk.) Mouthwash Formulation Inhibited Dental Plaque against Streptococcus mutans |
| title_short | The Antibacterial Activity of Bajakah Tampala Extracts (Spatholobus littoralis Hassk.) Mouthwash Formulation Inhibited Dental Plaque against Streptococcus mutans |
| title_sort | antibacterial activity of bajakah tampala extracts spatholobus littoralis hassk mouthwash formulation inhibited dental plaque against streptococcus mutans |
| topic | bajakah tampala antibacterial activity mouthwash herbal cosmetic streptococcus mutans |
| url | https://jurnal.ugm.ac.id/v3/JFPS/article/view/15147/4837 |
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