Vialess heterogeneous skin patch for multimodal monitoring and stimulation
Abstract System-level wearable electronics require to be flexible to ensure conformal contact with the skin, but they also need to integrate rigid and bulky functional components to achieve system-level functionality. As one of integration methods, folding integration offers simplified processing an...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-55951-6 |
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| author | Hyeokjun Lee Soojeong Song Junwoo Yea Jeongdae Ha Saehyuck Oh Janghwan Jekal Myung Seok Hong Chihyeong Won Han Hee Jung Hohyun Keum Sangyoon Han Jeong Ho Cho Taeyoon Lee Kyung-In Jang |
| author_facet | Hyeokjun Lee Soojeong Song Junwoo Yea Jeongdae Ha Saehyuck Oh Janghwan Jekal Myung Seok Hong Chihyeong Won Han Hee Jung Hohyun Keum Sangyoon Han Jeong Ho Cho Taeyoon Lee Kyung-In Jang |
| author_sort | Hyeokjun Lee |
| collection | DOAJ |
| description | Abstract System-level wearable electronics require to be flexible to ensure conformal contact with the skin, but they also need to integrate rigid and bulky functional components to achieve system-level functionality. As one of integration methods, folding integration offers simplified processing and enhanced functionality through rigid-soft region separation, but so far, it has mainly been applied to modality of electrical sensing and stimulation. This paper introduces a vialess heterogeneous skin patch with multi modalities that separates the soft region and strain-robust region through folded structure. Our system includes electrical and optical modalities for hemodynamic and cardiovascular monitoring, and a force-electrically driven micropump for drug delivery. Each modality is demonstrated through on-demand drug delivery, flexible waveguide-based PPG monitoring, and ECG and body movement monitoring. Wireless data transmission and real-time measurement validate the feedback operation for multi-modalities. This engineered closed-loop platform offers the possibility for broad applications, including cardiovascular monitoring and chronic disease management. |
| format | Article |
| id | doaj-art-0154ff76f4df4555a187bc1fe2ab6afa |
| institution | Kabale University |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-0154ff76f4df4555a187bc1fe2ab6afa2025-01-19T12:31:54ZengNature PortfolioNature Communications2041-17232025-01-0116111410.1038/s41467-025-55951-6Vialess heterogeneous skin patch for multimodal monitoring and stimulationHyeokjun Lee0Soojeong Song1Junwoo Yea2Jeongdae Ha3Saehyuck Oh4Janghwan Jekal5Myung Seok Hong6Chihyeong Won7Han Hee Jung8Hohyun Keum9Sangyoon Han10Jeong Ho Cho11Taeyoon Lee12Kyung-In Jang13Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST)Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST)Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST)Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST)Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST)Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST)ASML KoreaSchool of Electrical and Electronic Engineering, Yonsei UniversityDepartment of Information and Communication Engineering, Hannam UniversityIndustrial Transformation Technology Department, Korea Institute of Industrial Technology (KITECH)Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST)Department of Chemical and Biomolecular Engineering, Yonsei UniversitySchool of Electrical and Electronic Engineering, Yonsei UniversityDepartment of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST)Abstract System-level wearable electronics require to be flexible to ensure conformal contact with the skin, but they also need to integrate rigid and bulky functional components to achieve system-level functionality. As one of integration methods, folding integration offers simplified processing and enhanced functionality through rigid-soft region separation, but so far, it has mainly been applied to modality of electrical sensing and stimulation. This paper introduces a vialess heterogeneous skin patch with multi modalities that separates the soft region and strain-robust region through folded structure. Our system includes electrical and optical modalities for hemodynamic and cardiovascular monitoring, and a force-electrically driven micropump for drug delivery. Each modality is demonstrated through on-demand drug delivery, flexible waveguide-based PPG monitoring, and ECG and body movement monitoring. Wireless data transmission and real-time measurement validate the feedback operation for multi-modalities. This engineered closed-loop platform offers the possibility for broad applications, including cardiovascular monitoring and chronic disease management.https://doi.org/10.1038/s41467-025-55951-6 |
| spellingShingle | Hyeokjun Lee Soojeong Song Junwoo Yea Jeongdae Ha Saehyuck Oh Janghwan Jekal Myung Seok Hong Chihyeong Won Han Hee Jung Hohyun Keum Sangyoon Han Jeong Ho Cho Taeyoon Lee Kyung-In Jang Vialess heterogeneous skin patch for multimodal monitoring and stimulation Nature Communications |
| title | Vialess heterogeneous skin patch for multimodal monitoring and stimulation |
| title_full | Vialess heterogeneous skin patch for multimodal monitoring and stimulation |
| title_fullStr | Vialess heterogeneous skin patch for multimodal monitoring and stimulation |
| title_full_unstemmed | Vialess heterogeneous skin patch for multimodal monitoring and stimulation |
| title_short | Vialess heterogeneous skin patch for multimodal monitoring and stimulation |
| title_sort | vialess heterogeneous skin patch for multimodal monitoring and stimulation |
| url | https://doi.org/10.1038/s41467-025-55951-6 |
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