Effect of Laparoscopic Adjustable Gastric Banding on Metabolic Syndrome and Its Risk Factors in Morbidly Obese Adolescents

We examined the effect of laparoscopic adjustable gastric banding (LAGB) on weight loss, inflammatory markers, and components of the Metabolic Syndrome (MeS) in morbidly obese adolescents and determined if those with MeS lose less weight post-LAGB than those without. Data from 14–18 yr adolescents w...

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Main Authors: Rushika Conroy, Eun-Ju Lee, Amy Jean, Sharon E. Oberfield, Aviva Sopher, Krystina Kiefer, Courtney Raker, Donald J. McMahon, Jeffrey L. Zitsman, Ilene Fennoy
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2011/906384
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author Rushika Conroy
Eun-Ju Lee
Amy Jean
Sharon E. Oberfield
Aviva Sopher
Krystina Kiefer
Courtney Raker
Donald J. McMahon
Jeffrey L. Zitsman
Ilene Fennoy
author_facet Rushika Conroy
Eun-Ju Lee
Amy Jean
Sharon E. Oberfield
Aviva Sopher
Krystina Kiefer
Courtney Raker
Donald J. McMahon
Jeffrey L. Zitsman
Ilene Fennoy
author_sort Rushika Conroy
collection DOAJ
description We examined the effect of laparoscopic adjustable gastric banding (LAGB) on weight loss, inflammatory markers, and components of the Metabolic Syndrome (MeS) in morbidly obese adolescents and determined if those with MeS lose less weight post-LAGB than those without. Data from 14–18 yr adolescents were obtained at baseline, 6 and 12 months following LAGB. Significant weight loss and improvements in MeS components were observed 6 months and one year following LAGB. The incidence of MeS declined 56.8% after 6 months and 69.6% after 12 months. There was no significant difference in amount of weight lost post-LAGB between those with and without MeS at either timepoint. Correlations between change in weight parameters and components of MeS in those with and without MeS at baseline were examined and found to vary by diagnostic category. LAGB is effective for short-term improvement in weight, inflammatory markers, and components of MeS in morbidly obese adolescents.
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spelling doaj-art-01441218ae164fdfb50f55116545af5a2025-02-03T05:46:46ZengWileyJournal of Obesity2090-07082090-07162011-01-01201110.1155/2011/906384906384Effect of Laparoscopic Adjustable Gastric Banding on Metabolic Syndrome and Its Risk Factors in Morbidly Obese AdolescentsRushika Conroy0Eun-Ju Lee1Amy Jean2Sharon E. Oberfield3Aviva Sopher4Krystina Kiefer5Courtney Raker6Donald J. McMahon7Jeffrey L. Zitsman8Ilene Fennoy9Division of Pediatric Endocrinology, Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, NY 10032, USADivision of Pediatric Endocrinology, Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, NY 10032, USADivision of Pediatric Endocrinology, Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, NY 10032, USADivision of Pediatric Endocrinology, Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, NY 10032, USADivision of Pediatric Endocrinology, Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, NY 10032, USADivision of Pediatric Endocrinology, Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, NY 10032, USADivision of Pediatric Endocrinology, Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, NY 10032, USADivision of Pediatric Endocrinology, Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, NY 10032, USADivision of Surgery, College of Physicians and Surgeons, Columbia University Medical Center, New York, NY 10032, USADivision of Pediatric Endocrinology, Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, NY 10032, USAWe examined the effect of laparoscopic adjustable gastric banding (LAGB) on weight loss, inflammatory markers, and components of the Metabolic Syndrome (MeS) in morbidly obese adolescents and determined if those with MeS lose less weight post-LAGB than those without. Data from 14–18 yr adolescents were obtained at baseline, 6 and 12 months following LAGB. Significant weight loss and improvements in MeS components were observed 6 months and one year following LAGB. The incidence of MeS declined 56.8% after 6 months and 69.6% after 12 months. There was no significant difference in amount of weight lost post-LAGB between those with and without MeS at either timepoint. Correlations between change in weight parameters and components of MeS in those with and without MeS at baseline were examined and found to vary by diagnostic category. LAGB is effective for short-term improvement in weight, inflammatory markers, and components of MeS in morbidly obese adolescents.http://dx.doi.org/10.1155/2011/906384
spellingShingle Rushika Conroy
Eun-Ju Lee
Amy Jean
Sharon E. Oberfield
Aviva Sopher
Krystina Kiefer
Courtney Raker
Donald J. McMahon
Jeffrey L. Zitsman
Ilene Fennoy
Effect of Laparoscopic Adjustable Gastric Banding on Metabolic Syndrome and Its Risk Factors in Morbidly Obese Adolescents
Journal of Obesity
title Effect of Laparoscopic Adjustable Gastric Banding on Metabolic Syndrome and Its Risk Factors in Morbidly Obese Adolescents
title_full Effect of Laparoscopic Adjustable Gastric Banding on Metabolic Syndrome and Its Risk Factors in Morbidly Obese Adolescents
title_fullStr Effect of Laparoscopic Adjustable Gastric Banding on Metabolic Syndrome and Its Risk Factors in Morbidly Obese Adolescents
title_full_unstemmed Effect of Laparoscopic Adjustable Gastric Banding on Metabolic Syndrome and Its Risk Factors in Morbidly Obese Adolescents
title_short Effect of Laparoscopic Adjustable Gastric Banding on Metabolic Syndrome and Its Risk Factors in Morbidly Obese Adolescents
title_sort effect of laparoscopic adjustable gastric banding on metabolic syndrome and its risk factors in morbidly obese adolescents
url http://dx.doi.org/10.1155/2011/906384
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