Chlamydial entry involves TARP binding of guanine nucleotide exchange factors.
Chlamydia trachomatis attachment to cells induces the secretion of the elementary body-associated protein TARP (Translocated Actin Recruiting Protein). TARP crosses the plasma membrane where it is immediately phosphorylated at tyrosine residues by unknown host kinases. The Rac GTPase is also activat...
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| Main Authors: | B Josh Lane, Charla Mutchler, Souhaila Al Khodor, Scott S Grieshaber, Rey A Carabeo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-03-01
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| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000014&type=printable |
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