A copy number variation detection method based on OCSVM algorithm using multi strategies integration

A copy number variation detection method based on OCSVM algorithm using multi strategies integration

Abstract Copy number variation (CNV) is an important part of human genetic variations, which is associated with various kinds of diseases. To tackle the limitations of traditional CNV detection methods, such as restricted detection types, high error rates, and challenges in precisely identifying the...

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Bibliographic Details
Main Authors: Mengjiao Zhou, Jinxin Dong, Hua Jiang, Zuyao Zhao, Tianting Yuan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Copy number variations
Next-generation sequencing technology
One class support vector machine algorithm
Read depth
Split read
Pair-end mapping
Online Access:https://doi.org/10.1038/s41598-025-88143-9
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https://doi.org/10.1038/s41598-025-88143-9

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