Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding
Introduction. Primary lymphoma of the gallbladder is an extremely rare entity with approximately 50 cases reported so far. In many of these cases the presenting symptoms were mimicking symptomatic gallstone disease and the diagnosis was made postoperatively, especially when the preoperative imaging...
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| Format: | Article |
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Wiley
2014-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2014/716071 |
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| author | Kyriakos Psarras Nikolaos Symeonidis Euthymia Vlachaki Minas Baltatzis Georgios Papatolios Efstathios Pavlidis Christina Mouratidou Ioannis Venizelos Theodoros Pavlidis Athanasios Sakantamis Christina Nikolaidou |
| author_facet | Kyriakos Psarras Nikolaos Symeonidis Euthymia Vlachaki Minas Baltatzis Georgios Papatolios Efstathios Pavlidis Christina Mouratidou Ioannis Venizelos Theodoros Pavlidis Athanasios Sakantamis Christina Nikolaidou |
| author_sort | Kyriakos Psarras |
| collection | DOAJ |
| description | Introduction. Primary lymphoma of the gallbladder is an extremely rare entity with approximately 50 cases reported so far. In many of these cases the presenting symptoms were mimicking symptomatic gallstone disease and the diagnosis was made postoperatively, especially when the preoperative imaging results were far from suspicious for malignant disease. Patients and Methods. We report a case of primary lymphoma of the gallbladder in an 85-year-old man with gallstone disease, who was admitted for elective cholecystectomy 2 months after an episode of acute cholecystitis and pancreatitis. Histological evaluation of the specimen revealed a small lymphocytic lymphoma of the gallbladder. This type of primary gallbladder lymphoma has not been previously reported. Discussion. The most common primary lymphomas of the gallbladder are MALT lymphomas and diffuse large B-cell lymphomas, although a variety of other histological types have been reported. The association of these lesions with chronic inflammation is the most convincing theory for their pathogenesis. For lesions confined to the gallbladder, cholecystectomy is considered to be sufficient, while supplementary chemotherapy significantly improves prognosis in more advanced disease. |
| format | Article |
| id | doaj-art-01226466a02a441aba810296ac1b09c7 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-01226466a02a441aba810296ac1b09c72025-02-03T05:51:23ZengWileyCase Reports in Hematology2090-65602090-65792014-01-01201410.1155/2014/716071716071Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy FindingKyriakos Psarras0Nikolaos Symeonidis1Euthymia Vlachaki2Minas Baltatzis3Georgios Papatolios4Efstathios Pavlidis5Christina Mouratidou6Ioannis Venizelos7Theodoros Pavlidis8Athanasios Sakantamis9Christina Nikolaidou102nd Department of Propedeutical Surgery, School of Health Sciences, Aristotle University of Thessaloniki, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, Greece2nd Department of Propedeutical Surgery, School of Health Sciences, Aristotle University of Thessaloniki, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, Greece2nd Department of Internal Medicine, School of Health Sciences, Aristotle University of Thessaloniki, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, Greece2nd Department of Propedeutical Surgery, School of Health Sciences, Aristotle University of Thessaloniki, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, Greece2nd Department of Propedeutical Surgery, School of Health Sciences, Aristotle University of Thessaloniki, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, Greece2nd Department of Propedeutical Surgery, School of Health Sciences, Aristotle University of Thessaloniki, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, Greece2nd Department of Propedeutical Surgery, School of Health Sciences, Aristotle University of Thessaloniki, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, GreeceDepartment of Pathology, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, Greece2nd Department of Propedeutical Surgery, School of Health Sciences, Aristotle University of Thessaloniki, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, Greece2nd Department of Propedeutical Surgery, School of Health Sciences, Aristotle University of Thessaloniki, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, GreeceDepartment of Pathology, Hippokratio General Hospital, 49 Konstantinoupoleos Street, 54642 Thessaloniki, GreeceIntroduction. Primary lymphoma of the gallbladder is an extremely rare entity with approximately 50 cases reported so far. In many of these cases the presenting symptoms were mimicking symptomatic gallstone disease and the diagnosis was made postoperatively, especially when the preoperative imaging results were far from suspicious for malignant disease. Patients and Methods. We report a case of primary lymphoma of the gallbladder in an 85-year-old man with gallstone disease, who was admitted for elective cholecystectomy 2 months after an episode of acute cholecystitis and pancreatitis. Histological evaluation of the specimen revealed a small lymphocytic lymphoma of the gallbladder. This type of primary gallbladder lymphoma has not been previously reported. Discussion. The most common primary lymphomas of the gallbladder are MALT lymphomas and diffuse large B-cell lymphomas, although a variety of other histological types have been reported. The association of these lesions with chronic inflammation is the most convincing theory for their pathogenesis. For lesions confined to the gallbladder, cholecystectomy is considered to be sufficient, while supplementary chemotherapy significantly improves prognosis in more advanced disease.http://dx.doi.org/10.1155/2014/716071 |
| spellingShingle | Kyriakos Psarras Nikolaos Symeonidis Euthymia Vlachaki Minas Baltatzis Georgios Papatolios Efstathios Pavlidis Christina Mouratidou Ioannis Venizelos Theodoros Pavlidis Athanasios Sakantamis Christina Nikolaidou Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding Case Reports in Hematology |
| title | Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding |
| title_full | Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding |
| title_fullStr | Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding |
| title_full_unstemmed | Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding |
| title_short | Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding |
| title_sort | primary gallbladder small lymphocytic lymphoma as a rare postcholecystectomy finding |
| url | http://dx.doi.org/10.1155/2014/716071 |
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