Phytochemical and Metabolomic Investigation of a Popular Traditional Plant from La Réunion: <i>Psiloxylon mauritianum</i>
A molecular network investigation of <i>Psiloxylon mauritianum</i> leaf extracts from five different specimens led to the detection of a diversity of flavonoids, triterpenes, and phloroglucinols. Some compounds from these molecular classes are reported to target fever-linked symptoms (an...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
|
| Series: | Applied Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3417/15/2/496 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | A molecular network investigation of <i>Psiloxylon mauritianum</i> leaf extracts from five different specimens led to the detection of a diversity of flavonoids, triterpenes, and phloroglucinols. Some compounds from these molecular classes are reported to target fever-linked symptoms (antioxidant, antiviral, anti-inflammatory, and antibacterial activities) and may explain the plant’s success as a local traditional remedy. The phytochemical study of one extract allowed the isolation and characterization of an original seco-ring-A lupane structurally similar to the anti-inflammatory betulinic acid, 11 known triterpenes, 2 flavonoids, and a chalcone. Antiviral assays highlighted the in vitro anti-Zika activity of corosolic and betulinic acids found in the plant. Some interesting structure–activity relationships could be drawn between the new compound and the known active triterpenes. |
|---|---|
| ISSN: | 2076-3417 |