Lidocaine could promote the cuproptosis through up-regulating the long noncoding RNA DNMBP-AS1 in Hep-2 cells

Lidocaine could promote the cuproptosis through up-regulating the long noncoding RNA DNMBP-AS1 in Hep-2 cells

Abstract Background Lidocaine is a traditional local anesthetic, which has been reported to trigger apoptosis through the mitochondrial pathway, independent of death receptor signaling. Cuproptosis is a copper triggered mitochondrial cell death mode. In this study, we explored the biological effects...

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Bibliographic Details
Main Authors: Wei Liu, Yi Yu, Yi He, Meihong Lv
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
Subjects:
Lidocaine
Hep-2 cells
Cuproptosis
IncRNA DNMBP-AS1
Online Access:https://doi.org/10.1186/s12885-025-13533-1
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