ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism

ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism

Abstract Background Prostate cancer (PrCa) is a significant health concern, ranking as the second most common cancer in males globally. Genetic factors contribute substantially to PrCa risk, with up to 57% of the risk being attributed to genetic determinants. A major challenge in managing PrCa is th...

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Bibliographic Details
Main Authors: Christoffer Löf, Nasrin Sultana, Neha Goel, Samuel Heron, Gudrun Wahlström, Andrew House, Minna Holopainen, Reijo Käkelä, Johanna Schleutker
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cell Communication and Signaling
Subjects:
Prostate cancer
ANO7
Mitochondria
Lipid metabolism
MYC
OXPHOS
Online Access:https://doi.org/10.1186/s12964-025-02081-7
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