QSAR Studies of 6-Amino Uracil Base Analogues: A Thymidine Phosphorylase Inhibitor in Cancer Therapy

QSAR Studies of 6-Amino Uracil Base Analogues: A Thymidine Phosphorylase Inhibitor in Cancer Therapy

A novel series of 6-amino uracil base analogue were synthesized. QSAR study was used to relate the selective nonsubstrate inhibitory activity of 6-amino uracil base analogue with various physicochemical descriptors. Stepwise multiple regression analysis was performed to find out the correlation bet...

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Bibliographic Details
Main Authors:	Surya Prakash B. N. Gupta, Neeraj Upmanyu, N. S. Hari Narayana Moorthy, S. Bhattacharya
Format:	Article
Language:	English
Published:	Wiley 2008-01-01
Series:	E-Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2008/242865
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